نتایج جستجو برای: photoacoustic imaging

تعداد نتایج: 459884  

Journal: :Physical review. E, Statistical, nonlinear, and soft matter physics 2007
Andrew R Fisher Andrew J Schissler John C Schotland

We consider the photoacoustic effect for multiply scattered light in a random medium. Within the accuracy of the diffusion approximation to the radiative transport equation, we present a general analysis of the sensitivity of a photoacoustic wave to the presence of one or more small absorbing objects. Applications to tumor detection by photoacoustic imaging are suggested.

Journal: :Journal of biomedical optics 2010
Roy G M Kolkman Erik Blomme Tijl Cool Mattias Bilcke Ton G van Leeuwen Wiendelt Steenbergen Kees A Grimbergen Gerard J den Heeten

The feasibility of air-coupled ultrasound transducers to detect laser-induced ultrasound from artificial blood vessels embedded in an optically scattering phantom is demonstrated. These air-coupled transducers allow new applications in biomedical photoacoustic imaging where contact with tissue is not preferred. One promising application of such transducers is the addition of photoacoustic imagi...

Journal: :Journal of the American Chemical Society 2010
Jelena Levi Sri Rajasekhar Kothapalli Te-Jen Ma Keith Hartman Butrus T Khuri-Yakub Sanjiv Sam Gambhir

Photoacoustic tomography is a rapidly growing imaging modality that can provide images of high spatial resolution and high contrast at depths up to 5 cm. We report here the design, synthesis, and evaluation of an activatable probe that shows great promise for enabling detection of the cleaved probe in the presence of high levels of nonactivated, uncleaved probe, a difficult task to attain in ab...

Journal: :Optics express 2010
Ragnar Olafsson Daniel R Bauer Leonardo G Montilla Russell S Witte

A clinical ultrasound scanner and 14 MHz linear array collected real-time photoacoustic images (PAI) during an injection of gold nanorods (GNRs) near the region of a mature PC-3 prostate tumor in mice implanted with a skin flap window chamber. Three dimensional spectroscopic PAI (690-900 nm) was also performed to investigate absorption changes near the tumor and enhance specific detection of GN...

2010
Lei Xi Jingjing Sun Yiping Zhu Lei Wu Huikai Xie Huabei Jiang

A microelectromechanical systems (MEMS)-based photoacoustic imaging system is reported for the first time. In this system, the MEMS-based light scanning subsystem and a ring-shaped polyvinylidene fluoride (PVDF) transducer are integrated into a miniaturized probe that is capable of three-dimensional (3D) photoacoustic imaging. It is demonstrated that the imaging system is able to image small ob...

2016
C. Hall A. Williams N. Wood

We describe a differential photoacoustic (PA) imaging system in which almost equal intensity beams modulated 180' out of phase illuminate two regions of a sample in a PA cell. For two regions that are both optically and thermally similar and also homogeneous, the resulting signal is almost zero but if one region has a sub-surface defect this will give an increased signal. This differential sign...

2017
Yun-Sheng Chen Soon Joon Yoon Wolfgang Frey Mary Dockery Stanislav Emelianov

Molecular photoacoustic imaging has shown great potential in medical applications; its sensitivity is normally in pico-to-micro-molar range, dependent on exogenous imaging agents. However, tissue can produce strong background signals, which mask the signals from the imaging agents, resulting in orders of magnitude sensitivity reduction. As such, an elaborate spectral scan is often required to s...

2016
Henry VanBrocklin Lisa Polin Jawana M. Lawhorn-Crews Thomas J. Mangner Mugdha Patki Shirish Gadgeel Larry Matherly Manohar Ratnam Suhail S. Alshahrani Yan Yan Rebecca Meerschaert Zichun Zhong Ling Zhuang Jiani Hu Alex Zhuang Jianjun Wang Qing Lu Haoyu Wang Yimin Shen Quan Jiang Nashaat Turkman David Gelovani Aleksandr Shavrin Xin Lu Thomas Mangner Juri Gelovani

With the growing applications of Photoacoustic Imaging (PAI) in neurology, vascular biology, dermatology, ophthalmology, tissue engineering, angiogenesis, and other medical specialties, there is a need to make the system more compact, portable and affordable. Therefore, we designed an economical and compact version of PAI systems by replacing expensive and sophisticated lasers with a robust pul...

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