نتایج جستجو برای: phosphatidylinositol kinase
تعداد نتایج: 233279 فیلتر نتایج به سال:
Type 2 diabetes mellitus (T2DM) is a complex metabolic disease threatening human health. We investigated the effects of Tegillarca granosa polysaccharide (TGP) and determined its potential mechanisms in mouse model T2DM established through high-fat diet streptozotocin. TGP (5.1×103 Da) was composed mannose, glucosamine, rhamnose, glucuronic acid, galactosamine, glucose, galact...
The Lank Center for Genitourinary Oncology, Department of Adult Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115 [A. E. P., P. W. K.]; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115 [M. J. S., E. G., J. M.]; and Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women’s Hospital...
It has been demonstrated that vasoactive intestinal polypeptide, epidermal growth factor, and chronic activation of phosphatidylinositol 3-kinase can protect prostate cancer cells from apoptosis; however, the signaling pathways that they use and molecules that they target are unknown. We report that vasoactive intestinal polypeptide, epidermal growth factor, and phosphatidylinositol 3-kinase ac...
Objective(s): Fibromyalgia (FM) is a central nervous system disorder characterized by widespread mechanical hyperalgesia due to unknown mechanisms. Several inflammatory mediators, such as interleukin-1 (IL-1), IL-6, IL-8, and tumor necrosis factor, are increased in the serum of FM patients. Although medications including pregabalin, duloxetine, and milnacipran are used...
Objective(s): Ulcerative colitis (UC) is a kind of complex immune disease, and a major cause of destruction of intestinal barrier and oxidative stress in this field. In this paper, glutamine (Gln) was believed to offer protection against oxidative stress injury in colitis mice.Materials and Methods: Thirty mice were randomly assigned int...
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