نتایج جستجو برای: phenotype plasticity

تعداد نتایج: 214520  

2007
Beverly I. Strassmann Ruth Mace

Phenotypic plasticity refers to variation in the phenotype that can be attributed to environmental differences rather than genetic differences (WestEberhard 2003); this definition does not, however, invoke the false dichotomy of ‘nature versus nurture.’ Nor does it mean that learning and other phenotypically plastic traits require less genetically transmitted information than do more canalized ...

2018
Pierre-Olivier Montiglio Joel W McGlothlin Damien R Farine

Organisms express phenotypic plasticity during social interactions. Interacting phenotype theory has explored the consequences of social plasticity for evolution, but it is unclear how this theory applies to complex social structures. We adapt interacting phenotype models to general social structures to explore how the number of social connections between individuals and preference for phenotyp...

Journal: :PLoS Genetics 2007
Jean-Michel Gibert Frédérique Peronnet Christian Schlötterer

Phenotypic plasticity is the ability of a genotype to produce contrasting phenotypes in different environments. Although many examples have been described, the responsible mechanisms are poorly understood. In particular, it is not clear how phenotypic plasticity is related to buffering, the maintenance of a constant phenotype against genetic or environmental variation. We investigate here the g...

2014
J. A. Stamps V. V. Krishnan

*Correspondence: J. A. Stamps, Evolution and Ecology, University of California Davis, 1 Shields Ave, Davis, CA 95616, USA e-mail: [email protected] Changes in personality over ontogeny can occur even when every agent (individual or genotype) is exposed to the same set of cues, experiences or environmental conditions. A recent Bayesian model (Stamps and Krishnan, in press) shows how individua...

Journal: :Neuropharmacology 2015
Raasay S Jones Marina A Lynch

Microglia are particularly plastic cells which can be shifted from their resting state by numerous factors and adopt distinct phenotypes. The cells are multifunctional, though their main role is probably maintenance of homoeostasis. Resting cells are responsible for surveillance, whereas activation induces the cells to adopt neuroprotective or neurodetrimental roles, which are anti-inflammatory...

2017
Reinoud Gosens Johan Zaagsma Mechteld Grootte Bromhaar Adriaan Nelemans Herman Meurs

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Heiko Wurdak Shoutian Zhu Kyung Hoon Min Lindsey Aimone Luke L Lairson James Watson Gregory Chopiuk James Demas Bradley Charette Rajkumar Halder Eranthie Weerapana Benjamin F Cravatt Hollis T Cline Eric C Peters Jay Zhang John R Walker Chunlei Wu Jonathan Chang Tove Tuntland Charles Y Cho Peter G Schultz

Adult neurogenesis occurs in mammals and provides a mechanism for continuous neural plasticity in the brain. However, little is known about the molecular mechanisms regulating hippocampal neural progenitor cells (NPCs) and whether their fate can be pharmacologically modulated to improve neural plasticity and regeneration. Here, we report the characterization of a small molecule (KHS101) that se...

2010
Giuseppe Fusco Alessandro Minelli

This theme issue pursues an exploration of the potential of taking into account the environmental sensitivity of development to explaining the evolution of metazoan life cycles, with special focus on complex life cycles and the role of developmental plasticity. The evolution of switches between alternative phenotypes as a response to different environmental cues and the evolution of the control...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2012
Dawn A Kirschmann Elisabeth A Seftor Katharine M Hardy Richard E B Seftor Mary J C Hendrix

Tumor cell vasculogenic mimicry (VM) describes the functional plasticity of aggressive cancer cells forming de novo vascular networks, thereby providing a perfusion pathway for rapidly growing tumors, transporting fluid from leaky vessels, and/or connecting with endothelial-lined vasculature. The underlying induction of VM seems to be related to hypoxia, which may also promote the plastic, tran...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2007
Peter D Gluckman Karen A Lillycrop Mark H Vickers Anthony B Pleasants Emma S Phillips Alan S Beedle Graham C Burdge Mark A Hanson

Developmental plasticity in response to environmental cues can take the form of polyphenism, as for the discrete morphs of some insects, or of an apparently continuous spectrum of phenotype, as for most mammalian traits. The metabolic phenotype of adult rats, including the propensity to obesity, hyperinsulinemia, and hyperphagia, shows plasticity in response to prenatal nutrition and to neonata...

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