Eleven new bisresorcinols including four mixtures each of two isomers and one resorcinol/phloroglucinol derivative, together with five known resorcinols have been isolated from the ethyl acetate extract of stems of Grevillea whiteana. The new compounds were identified as 4-(3-hydroxy-3-methylbutyl)grebustol-B (10a), 4'-(3-hydroxy-3-methylbutyl)grebustol-B (10b), 4-(4-hydroxy-3-methylbutyl)grebu...

Our aim in this study was to provide further support to the hypothesis that phenolic compounds may play an important role in the anticarcinogenic properties of olive oil. We measured the effect of olive oil phenols on hydrogen peroxide (H(2)O(2))-induced DNA damage in human peripheral blood mononuclear cells (PBMC) and promyelocytic leukemia cells (HL60) using single-cell gel electrophoresis (c...

BACKGROUND Worldwide, Streptococcus pyogenes is the leading cause of bacterial pharyngitis. To reduce the use of antibiotics, antimicrobial phytochemical-containing remedies, which have long been in use in traditional medicine, may provide new approaches for management of streptococcal pharyngitis. The objective of this study was to assess the inhibitory activities of 25 natural phenolic compou...

background scrophularia striata (scrophulariaceae family) is an herbaceous plant that is traditionally used for treatment of microbial infections. objectives antimicrobial and antioxidant activity of different extracts (methanolic, ethanolic, aqueous and ethyl acetate) from s. striata aerial parts was evaluated. materials and methods the antimicrobial activity of different extracts from s. stri...

Phytochemistry and antioxidant activity of Amaranthus viridis L (Green leaf) were undertaken with standard methods. The leaf sample after being screening for phytochemicals, contained tannins, saponins, flavonoids, alkaloids, steroids, phenolic compounds, proteins anthraquinones at different concentrations. A further study using Gas Chromatography-Mass Spectrophotometry (GC-MS) analytic method ...

Although many benefits drawn from beer consumption are claimed, the epidemiological records contradictory with respect to cancer prevention. The purpose of this study was investigate possible health-related activities involving genome safety and ageing processes two types lyophilised ale beers (blond stout), as well their bioactive compounds (tyrosol iso-alpha humulone). A multipurpose trial se...

The objective of this investigation was to find a simple method for the production of phenolic rich products and sugar derivatives (biopolyols) via separation of liquefied lingocellulosic materials. Liquefaction of lignocellulosic materials was conducted in methanol at 180 °C for 15 min with the conversion of raw materials at about 75%. After liquefaction, the liquefied products were separated ...

We investigated the effects of phenolic and phenol compounds on 3,3',5-L-125I-triiodothyronine (125I-T3) binding to purified Xenopus laevis transthyretin (xTTR) and to the ligand-binding domain of X. laevis thyroid hormone receptor beta (xTR LBD), on T3-induced metamorphosis in X. laevis tadpoles and on the induction of T3-dependent reporter gene in a X. laevis cell line. Of the halogenated phe...

We isolated seven terpenes and five phenolic constituents from the aerial parts of Lactuca indica L. using column chromatographic separation of its MeOH extract. Their structures were determined by spectroscopic methods to be trans-phytol (1), 3beta-hydroxyglutin-5-ene (2), 5,6-epoxy-3-hydroxy-7-megastigmen-9-one (3), 11beta-13-dihydrolactucin (4), 2-phenylethyl beta-D-glucopyranoside (5), cich...

Two new mulinane-type derivatives: 16-hydroxy mulin-11,13-dien-20-oic (2) acid and 7alpha,16-dihydroxy mulin-11,13-dien-20-oic (3) acid were obtained by microbial transformation of mulin-11,13-dien-20-oic acid (1), along with tyrosol (4) using liquid cultures of Mucor plumbeus. The latter compound has not been previously identified in the genus Mucor. Structural elucidation of these metabolites...