Many studies have shown that pharmaceutical marketing affects prescribing choices. Studies that have assessed the effects of educational interventions on perceptions of pharmaceutical promotion have found mixed results. This study assesses the short-term effects of an educational intervention about marketing tactics on the attitudes and fund of knowledge of residents, medical students, and atte...

Ascorbic acid (AA) is a water-soluble vitamin which shows no fluorescence. However, in reaction with iron(III), AA is oxidised to dehydroascorbic acid and iron(III) is reduced to iron(II) which forms a complex with 2,4,6-tripyridyl-S-triazine (TPTZ) in buffered medium. The relative fluorescence intensity of the resulting Fe(TPTZ)₂(2+) complex can be measured at excitation and emission wavelengt...

Traditional pharmaceutical analysis is focused almost exclusively on the end products of manufacturing processes. Samples are taken from drug substance or drug product batches and analyzed in a remote laboratory. The samples typically go through stages of documentation, sample preparation, analysis, data analysis and documentation once more, prior to the reporting of the analytical results. Thi...

The electrochemical reduction of zanosar was investigated systematically by direct current polarography, cyclic voltammetry, and differential pulse polarography (DPP). A simple DPP technique was proposed for the direct quantitative determination of anticancer drug zanosar in pharmaceutical formulation and spiked human urine samples for the first time. The reduction potential was -0.28 V versus ...

Fecal coliform bacteria are widely used as indicators of sewage contamination in surface water. However, there are some disadvantages in these microbial techniques including time consuming (18-48h) and inability in discriminating between human and animal fecal material sources. Therefore, it is necessary to seek a more specific indicator of human sanitary waste. In this study, the feasibility w...

A practical protocol to obtain accurate heat capacity values of pharmaceutical compounds using modulated-temperature differential scanning calorimetry was established. Three pharmaceutical compounds, acetaminophen, indomethacin, and tri-O-methyl-β-cyclodextrin were used as model compounds. Powder samples did not produce reproducible results, presumably due to inclusion of gas in gap of powders ...

The aim of the study was to determine the effects of levofloxacin on the phagocytic and intracellular killing functions of human neutrophils at different therapeutic concentrations and to investigate the possible differences between pure powder and pharmaceutical form of levofloxacin on the neutrophil functions. Neutrophils obtained from healthy volunteers were incubated with both pure powder a...

Due to the severe consequences of potential overdoses paracetamol (PCM) on human body, measurement PCM in pharmaceutical and biological samples is essential.

Biological and pharmaceutical samples represent formidable challenges in sample preparation that hold important consequences for bioanalysis and genotoxic impurity quantification. This Feature will emphasize significant advances toward the development of rapid, sensitive, and selective sample preparation methods.

Monitoring the acetaminophen in biological samples and also in pharmaceutical formulations is important due to the concerns of public health care and drug safety. In this work a carbon paste electrode modified with BaTiO3 nanoparticle (BTO NPs) and room-temperature ionic liquid (IL) (n-hexyl-3-methylimidazolium hexafluoro phosphate) was fabricated. The direct electro-oxidation behavior of aceta...