LC-MS/MS is widely used in every stage of drug development, from discovery and characterization through manufacturing and quality control of the final pharmaceutical product. Due to its excellent selectivity for complex molecules, LC-MS/MS is an effective tool for both non-target qualitative analysis and quantitative analysis of targeted compounds. However, the sensitivity of LC-MS/MS varies si...

INTRODUCTION Little is known about the challenges facing the pharmaceutical sector in rural counties in the USA. The aim of this pilot study is to determine the main challenges facing the pharmaceutical sector and suggestions for improving the sector in Buchanan County, a poor and marginalized county in Central Appalachia, Virginia. METHODS This cross-sectional study used the drop-by survey b...

OBJECTIVE To assess the effectiveness of a product-analysis laboratory exercise in teaching students the importance of quality in pharmaceutical compounding. DESIGN Second-year pharmacy students (N=77) participated in a pharmaceutical compounding laboratory exercise and subsequently analyzed their final product using ultraviolet (UV) spectrometry. ASSESSMENT Reflection, survey instruments, ...

This study assessed agreement between two measures of medicine use, self-report by mail and pharmaceutical claims data, for a national sample (N = 4687) of older women aged 79 to 84 in 2005, from the Australian Longitudinal Study on Women’s Health. Medicines used for common chronic diseases in older people were selected, with pharmaceutical claims data retrieval periods of three and six months....

background: at the present time, teaching pharmacology for medical students mainly focuses on the basic principles of pharmacology. this study was conducted to assess the current situation of pharmacology teaching and the necessity of developing clinical pharmacology from the viewpoint of medical interns and externs in tabriz university of medical sciences. methods: this descriptive cross-secti...

Bromazepam are a well-known class of psychoactive drugs; they are known primarily for their hypnotic and sedative effects. In this recent research a very simple, precise, least time consuming, versatile, inexpensive and efficient UV Spectrophotometric method developed for the quantitation of Bromazepam in Active Pharmaceutical Ingredient and its pharmaceutical solid dosage formulation. The assa...

Aerosol drugs dominate a significant share of pharmaceutical preparations on the market. A novel sensitive method utilizing nano extractive electrospray ionization mass spectrometry (nanoEESI-MS) has been developed for the rapid analysis of aerosol drug samples with quantitative information. Without any sample pretreatment, aerosol drugs were manually sprayed into the primary ion plume created ...

A simple, precise, specific ,robust and rapid HPLC assay for the of measurement meloxicam in pharmaceutical formulations was developed and validated at Department of Pharmacy and Central Quality Assurance Laboratory, LCWU, Lahore. The solution of meloxicam standard was prepared in HPLC grade acetonitrile (5 μg.mL) and ultra sonicated for 15 minutes. One mL sample mixed well with one mL of HPLC ...

Plastic microfluidic array platforms and synergistic multiplexed assay chemistries are under development for a variety of applications, including assays of gene expression, proteomics, genotyping, DNA sequencing and fragment analysis, sample preparation and high-throughput pharmaceutical discovery. The low production costs of plastic substrates makes possible economical single-use device arrays...