Hot-melt extrusion is one of the most widely applied processing technologies in the plastic, rubber and food industry. Today this technology has found its place in the array of pharmaceutical manufacturing operations. Melt extrusion process are currently applied in the pharmaceutical field for the manufacture of a variety of dosage forms and formulations such as granules, pellets, tablets, supp...

The relationship between the pharmaceutical industry and physicians is evermore complex and has called attention on both sides. It is evident that, for many, medical ethics, both in dealings and empathy with patients as with the relationship between the pharmaceutical industry and the government, which in their current state are undesirable. Therefore, there is an urgent need for guidelines tha...