The purpose of this paper is to stimulate discussion around the thought processes and activities that occur from creation through development and commercialization of a molecule that ultimately becomes a drug product that benefits patients. This includes exploring the scientific evidence and pharmacological underpinnings that link clinical concepts to drug product design, manufacturing controls...

In the pharmaceutical world, an impurity is considered as any other organic material, besides the drug substance, or ingredients, arise out of synthesis or unwanted chemicals that remains with API’s. Impurity profiling is the process of acquiring and evaluating data that establishes biological safety of an individual impurity; thus, revealing its need and scope in pharmaceutical research. The c...

BACKGROUND Sex and gender sensitive inquiry is critical in pharmaceutical policy due to the sector's historical connection with women's health issues and due to the confluence of biological, social, political, and economic factors that shape the development, promotion, use, and effects of medicinal treatments. A growing number of research bodies internationally have issued laws, guidance or enc...

after the boom of pharmacological research during the 1950s, mainly as a result of the screening technique, the identification of active molecules, their reshaping by means of pharmaco-chemical drug design, and the creation of extremely efficacious and successful medicines, the pharmaceutical world sought a new source of inspiration. such biota as the tropical forest, a quantity of plants credi...