Consistent accumulation of petroleum hydrocarbon (PH) in soil and sediments is a big concern and, thus, warrants static technology to continuously remediate PH-contaminated soil. Bioelectrochemical systems (BESs) can offer the desired solution using inimitable metabolic response electroactive microbes without involving physiochemical process. To date, wide range BES-based applications for PH bi...

Acid pH often triggers changes in gene expression. However, little is known about the identity of the gene products that sense fluctuations in extracytoplasmic pH. The Gram-negative pathogen Salmonella enterica serovar Typhimurium experiences a number of acidic environments both inside and outside animal hosts. Growth in mild acid (pH 5.8) promotes transcription of genes activated by the respon...

Introduction HIF-induced tumor neovascularization has become an important target of anticancer therapy. While the current use of angiogenesis inhibitors aims at converting cancer to a chronic manageable disease [1], further modifications of the hypoxic tumor microenvironment are needed to achieve complete tumor regression. It has previously been proposed to take advantage of the increased produ...

Conventional methods for detecting ornithine decarboxylase activity require an extended period of incubation. However, with a few simple modifications, accurate results were obtained within a few hours rather than several days. The broth medium was modified, primarily by omitting glucose and by decreasing the pH to 5.5. A 1-ml amount of this broth was inoculated with one colony and then overlai...

ph control is a challenging problem due to its highly nonlinear nature. in this paper the performances of two different adaptive global linearizing controllers (glc) are compared. least squares technique has been used for identifying the titration curve. the first controller is a standard glc based on material balances of each species. for implementation of this controller a nonlinear state est...

Chemical modifications of rye seed chitinase-c (RSC-c) with yarious reagents suggested the inyolyements of tryptophan and glutamiclaspartic acid residues in the activity. Of these, the modification of tryptophan residues wjth ?V・bromosuccinimide (NBS) was inyestigated in detail. In the NBS-oxidation at pH 4.0, two of the six tryptophan residues in RSC-c were rapidly oxidized and the chitinase a...

One advantage of using protons for signaling and regulation as opposed to posttranslational modifications or cofactors is the potential for extremely rapid temporal responses. Protons can diffuse through water exceptionally quickly (“Grotthuss diffusion,” made possible in part by the quantum mechanical tunneling ability of protons), possibly facilitated by short-range motion in proteins (58). T...