La pandémie de Covid 19 à partir janvier 2020 - depuis la Chine vers le reste l’Asie, puis l’Europe et l’Afrique, enfin les deux Amériques -, n’est pas sans rappeler des épidémies du passé, souvent bien plus meurtrières encore, en premier lieu celles peste (qui emporta tiers population européenne 1348). Trois ont frappé travers l’histoire : Peste Justinien (541-770), Noire (1348-1352, suivie no...

La pandémie de Covid 19 à partir janvier 2020 - depuis la Chine vers le reste l’Asie, puis l’Europe et l’Afrique, enfin les deux Amériques -, n’est pas sans rappeler des épidémies du passé, souvent bien plus meurtrières encore, en premier lieu celles peste (qui emporta tiers population européenne 1348). Trois ont frappé travers l’histoire : Peste Justinien (541-770), Noire (1348-1352, suivie no...

Peste des petits ruminants virus (PPRV) causes the acute, highly contagious disease peste des petits ruminants (PPR) that affects small domestic and wild ruminants. PPR is of importance in the small livestock-keeping industry in Tanzania, especially in rural areas as it is an important source of livelihood. Morbidity and case fatality rate can be as high as 80-100% in naïve herds; however, in e...

Small ruminants infected with peste des petits ruminants virus exhibit lesions typical of epithelial infection and necrosis. However, the only established host receptor for this virus is the immune cell marker signaling lymphocyte activation molecule (SLAM). We have confirmed that the ovine Nectin-4 protein, when overexpressed in epithelial cells, permits efficient replication of PPRV. Furtherm...

Peste des petits ruminants (PPR) is an acute, febrile, viral disease of small ruminants that has a significant economic impact. For many viral diseases, vaccination with virus-like particles (VLPs) has shown considerable promise as a prophylactic approach; however, the processes of assembly and release of peste des petits ruminants virus (PPRV) VLPs are not well characterized, and their immunog...

Peste des petits ruminants (PPR) is a notifiable and reportable disease recognised by the Office Internationale Epizooties (OIE) penned for eradication 2030. It an endemic devastating of small in some countries Africa, Asia, Middle East. The militates against ruminant production increased flock numbers region. Information literature on current review was especially obtained compiled from CABI a...