In the colour-polymorphic Midas cichlid fish species complex (Amphilophus citrinellus spp.), gold morphs occur at much lower frequencies (< 10%) than dark individuals. This might be surprising because gold coloration is dominant and coded for by a single Mendelian locus. Furthermore, gold individuals are considered to be competitively advantaged over dark ones because they grow faster and win a...

Integrin alpha(V)beta(3) binds to extracellular matrix proteins through the tripeptide Arg-Gly-Asp (RGD), forming a shallow crevice rather than a deep binding pocket. A dynamic picture of how the RGD-alpha(V)beta(3) complex resists dissociation by mechanical force is derived here from steered molecular dynamic (SMD) simulations in which the major force peak correlates with the breaking of the c...

We have built a multiuser storage system named MIDAS (Multiuser Index-based Data Access System) which is intended to be used for a lower subsystem of database management systems running on UNIX. MIDAS implements a modified B+-tree structure for the sake of control of concurrent operations on a B+-tree index. To guarantee the more concurrent accesses to the system tables such as buffers, lock ta...

Cichlid fishes are an ideal model system for studying biological diversification because they provide textbook examples of rapid speciation. To date, there has been little focus on the role of gene regulation during cichlid speciation. However, in recent years, gene regulation has been recognized as a powerful force linking diversification in gene function to speciation. Here, we investigated t...

The International Rosetta Mission is set for a rendezvous with Comet 67 P/ChuryumovGerasimenko in 2014. On its 10 year journey to the comet, the spacecraft will also perform a fly-by of the two asteroids Stein and Lutetia in 2008 and 2010, respectively. The mission goal is to study the origin of comets, the relationship between cometary and interstellar material and its implications with regard...

Established empirical cases of sympatric speciation are scarce, although there is an increasing consensus that sympatric speciation might be more common than previously thought. Midas cichlid fish are one of the few substantiated cases of sympatric speciation, and they formed repeated radiations in crater lakes. In contrast, in the same environment, such radiation patterns have not been observe...

This paper documents current efforts to infuse human reliability analysis (HRA) into human performance simulation. The Idaho National Laboratory is teamed with NASA Ames Research Center to bridge the SPAR-H HRA method with NASA’s Man-machine Integration Design and Analysis System (MIDAS) for use in simulating and modeling the human contribution to risk in nuclear power plant control room operat...

Many applications today are highly data intensive and have stringent performance requirements. In order to meet the performance demands of these applications, we need to optimize both the processing and I/O subsystems. One promising approach to optimize performance is to use “Active Storage” systems, where we use disk drive controllers and storage array controllers as offload processors for the...

Persian is one of the Indo-European languages which has borrowed its script from Arabic, a member of Semitic language family. Since Persian and Arabic scripts are so similar, problems arise when we want to process an electronic text. In this paper, some of the common problems faced experimentally in developing a corpus for Persian are discussed. The sources of the problems are the Persian scrip...

In 802.11 managed wireless networks, the manager can address under-served links by rate-limiting the conflicting nodes. In order to determine to what extent each conflicting node is responsible for the poor performance, the manager needs to understand the coordination among conflicting nodes’ transmissions. In this paper, we present a management framework called MIDAS (Management, Inference, an...