The intestinal peristaltic reflex induced by mucosal stimulation is mediated by mucosal release of serotonin (5-HT), which acts on 5-HT(4) receptors located on CGRP-containing afferent nerve terminals. Exposure of the colonic mucosa to the 5-HT(4) receptor agonist tegaserod in the range of 1 nM to 10 muM elicits a peristaltic reflex and stimulates colonic propulsion. The present study was desig...

Abstract Particle dispersion in a two-dimensional peristaltic flow with zero pressure rise is investigated. It is found that, depending on the degree of occlusion of the peristalsis, particle motion can be forward or retrograde. Dispersion of a group of particles is quantified using the mean particle position and the variance around this. The degree of occlusion of the wave can be used to promo...

The primary objective of present investigation is to introduce the novel aspect of thermophoresis in the mixed convective peristaltic transport of viscous nanofluid. Viscous dissipation and Joule heating are also taken into account. Problem is modeled using the lubrication approach. Resulting system of equations is solved numerically. Effects of sundry parameters on the velocity, temperature, c...

A novel nano-scale pump that can transport atoms or small molecules with a peristaltic motion is designed. It proven by molecular-dynamics simulations the introduced nano-pump design works properly. The designed consists of one main carbon nanotube named flow tube and two rotors where multi-walled nanotubes are attached. pumping helium investigated simulations. For varying rotor speeds blade co...

BACKGROUND Perioperative fluid restriction might be beneficial in specific clinical settings. In this prospective, randomized and blinded study, we assessed whether peristaltic pneumatic compression of the legs can support restrictive fluid management strategies by reducing intraoperative fluid demand and improving hemodynamic stability. METHODS Seventy patients scheduled for minor surgery we...

Peristaltic pumps are mechanical displacement pumps that induce flow in a fluid-filled, flexiblewalled conduit through peristalsis – transport due to traveling contraction waves. While macroscale peristaltic pumps appear in a variety of configurations, micropumps based on this principle almost exclusively use the sequenced contraction and expansion of a small number of discrete actuators – typi...