Peripheral nerve injuries are common, and there is no easily available formula for successful treatment. Incomplete injuries are most frequent. Seddon classified nerve injuries into three categories: neurapraxia, axonotmesis, and neurotmesis. After complete axonal transection, the neuron undergoes a number of degenerative processes, followed by attempts at regeneration. A distal growth cone see...

malignant peripheral nerve sheath tumor (mpnst) is a rare malignant tumor that develops either from a preexisting neurofibroma or de novo. the cell of origin is believed to be the schwann cell and possibly other nerve sheath cells. in this report, we describe a rare case of mpnst that arise from the socket of second left maxillary molar that has been already extracted in a young man. he was ref...

Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair. This article reviews recent research progress of the role of neural stem cells in the repair of peripheral nerve injury. Neural stem cells can not only differentiate into neurons, astrocytes and ol...

how to cite this article: harsh v, chengazhacherril r.b, sharmak, kalakoti p, gupta u, ahmad w, kumar a. sciatic nerve injection palsy in children. iran j child neurol. autumn 2016; 10(4):86-87.   letter to editor  pls see pdf file.   references 1. toopchizadeh v, barzegar m, habibzadeh a. sciatic nerve injection palsy in children, electrophysiologic pattern and outcome: a case series study. ir...

Peripheral nerve injury is a common and devastating complication after trauma and can cause irreversible impairment or even complete functional loss of the affected limb. While peripheral nerve repair results in some axonal regeneration and functional recovery, the clinical outcome is not optimal and research continues to optimize functional recovery after nerve repair. Cell transplantation app...

Peripheral nervous system (PNS) is a complex construction, which serves dual purpose. Firstly, it disseminates information from the central nervous systems and ensures that this information is interpreted to the target end organs. Secondly, it collects information from the periphery, translates it to nerve signals, processes it and feeds it back to the central nervous system. The PNS consists o...

Peripheral nerve injury is a common clinical problem. Nerve growth factor (NGF) promotes peripheral nerve regeneration, but its clinical applications are limited by several constraints. In this study, we found that the time-dependent expression profiles of eight let-7 family members in the injured nerve after sciatic nerve injury were roughly similar to each other. Let-7 microRNAs (miRNAs) sign...

The repair of peripheral nerve injury has always been a difficult clinical problem. Although variety treatment methods are available in practice, their efficacy is limited. In recent years, the components carried by adipose stem cell exosomes and functions have increasingly discovered. A large number experiments conducted around world shown that adipose-derived positive effect on injury. This a...

Diseases and injuries to the nervous system can lead to a devastating chronic pain condition called neuropathic pain. We review changes that occur in the peripheral nervous system that may play a role in this disease. Common animal models for neuropathic pain involve an injury to one or more peripheral nerves. Following such an injury, the nerve fibers that have been injured exhibit many abnorm...