malignant peripheral nerve sheath tumor (mpnst) is a rare malignant tumor that develops either from a preexisting neurofibroma or de novo. the cell of origin is believed to be the schwann cell and possibly other nerve sheath cells. in this report, we describe a rare case of mpnst that arise from the socket of second left maxillary molar that has been already extracted in a young man. he was ref...

background: the standard method for repair of an injured peripheal nerve is epineural repair with separate sutures. herein we describe a method in which the nerve is sutured with continous sutures. in fact this method has not been utilized for nerve repair previously and our purpose was to compare it to the standard method. if it proved to be successful it would replace the standard method in c...

Background: Peripheral arterial disease is a source of morbidity and mortality. Surgical vascular reconstruction is a treatment option but probability of failure and complications are important concerns. In this study, we evaluated outcome of surgical infrainguinal reconstruction and factors affecting graft patency for a period of one year. Methods: In this cohort study, 85 consecutive patie...

PURPOSE Peripheral neuropathy (PN) is known as a major contributor of the worsening of ischemic symptoms and the foot ulceration in patients with peripheral arterial occlusive disease (PAOD). However, there are few studies reporting the prevalence and risk factors for PN in PAOD. This study aimed to evaluate these issues for PN and to establish the importance of screening as additional treatmen...

MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...

despite promising results observed using silicone rubber chamber, no previous comprehensive work was performed on behavior of the conduit. present study aimed at further functional, histomorphometrical and immunohistochemical assessment of nerve regeneration in the same animal along a 10-mm rat sciatic nerve gap. fifty- four male wistar rats were divided into three experimental groups (n = 18),...

malignant peripheral nerve sheath tumor (mpnst) is a rare nerve sheath tumor derived from schwann cells or pleuripotent cells of neural crest. neurogenic tumors make about 10-20% of all mediastinal tumors. incidence of mpnst is 0.001% in general population and 0.16% in patients with neurofibromatosis i (nf i). we report a case of 60 year female presenting with progressive cough and breathlessne...

introduction: peripheral odontogenic tumors are rare and there is no valid information of the frequency of them in the literature. this study aims to obtain the frequency of these tumors. materials and methods: the files of oral and maxillofacial pathology (microscopic reports and slides), faculty of dentistry, shahid beheshti university of medical sciences served as the source of the material ...

background lichen planus is a disease with unknown etiology that affects the skin and the mucous membranes. immune dysregulation in the pathogenesis of oral lichen planus (olp) is well-known phenomenon. objectives in this study, we compared the levels of the peripheral blood t lymphocytes between patients with olp and control group. patients and methods in this study, 32 and 16 patients respect...