The iron(II) complexes and with pentadentate pyridyl ligands are stable under physiological conditions and exhibit higher cytotoxicities toward a series of human carcinoma cell lines than cisplatin; can significantly increase intracellular oxidant levels, cleave supercoiled plasmid DNA in vitro without addition of a reductant and induce apoptotic cell death in human cervical epithelioid carcino...

Four copper(II) complexes with the ligands bearing two or three alkylpyridine pendant arms attached to an ethylene diamine framework were isolated in pure form (four-coordinate species as perchlorates, and five-coordinate species as hexafluorophosphates). Three complexes and one tosylated ligand were characterized by X-ray diffraction. In the absence of additional monoor bidentate ligands, line...

Investigations on a series of eight novel mononuclear iron(III) Schiff base complexes with the general formula [Fe(L(5))(L(1))]·S (where H(2)L(5) = pentadentate Schiff-base ligand, L(1) = a pseudohalido ligand, and S is a solvent molecule) are reported. Several different aromatic 2-hydroxyaldehyde derivatives were used in combination with a non-symmetrical triamine 1,6-diamino-4-azahexane to sy...

The two new ligands L(fur) and L(th) consist of two chelating pyrazolyl-pyridine termini connected to furan-2,5-diyl or thiophene-2,5-diyl spacers via methylene groups. Reaction of these with a range of transition metal dications that prefer octahedral coordination affords a series of unusual structures which are all based on a 2M : 3L ratio. [M(8)(L(fur))(12)]X(16) (M = Co, Cu, X = BF(4); and ...

Pentadentate electron rich MePBITA ligand in [RuII(MePBITA)(NO)]n+ (n = 3, 2 and 1-(6-(1-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine) permits the isolation of both redox states nitrosyls with Enemark–Feltham notation {RuNO}6 {RuNO}7. The nitrosyl derivative [RuII(MePBITA)(NO)](ClO4)3: [4](ClO4)3 was synthesized by stepwise synthetic manner from chloro pr...