Pemphigus vulgaris and mucous membrane pemphigoid are uncommon dermatological disorders which also involves the mucosae of the oral cavity. Both the conditions differ in microscopy and prognosis. Thus the aim of the present paper is to present one case each of pemphigus vulgaris and mucous membrane pemphigoid with oral involvement. Special attention has been made on the clinical tests to evalua...

A single cycle of rituximab for the treatment of severe pemphigus. Treatment of severe pemphigus with rituximab: report of 12 cases and a review of the literature. Clinical efficacy of different doses of ritux-imab in the treatment of pemphigus: a retrospective study of 27 patients. Rituximab for treatment-refractory pemphigus and pemphigoid: a case series of 17 patients. in autoim-mune bullous...

BACKGROUND Pemphigus is part of a group of blistering diseases that affect the skin and mucous membranes. Based on its autoimmune origin, autoantibodies develop in pemphigus that are directed toward cell surface components of keratinocytes. However, some data cannot be explained, such as the lack of a relationship between autoantibody levels and the severity of clinical manifestations, treatmen...

Pemphigus Vegetans was first described as a variant of Pemphigus Vulgaris in 1876 by Neumann. In 1889, Hallopeau described a patient with pustules and vegetating plaques, suggesting that it would be a variant of Pemphigus Vegetans of Neumann. Both types of Pemphigus Vegetans are characterized by the development of vegetating plaques especially on skin folds (axillae, groin, perianal region). Th...

Bullous Pemphigus and Pemphigus Vulgaris are autoimmune dermatological illnesses that manifest particularly in adults. They are characterized by the presence of auto-antibodies against specific structures of the skin and mucous membranes marked by the appearance of epithelial beads. While Bullous Pemphigus is of limited duration and is generally benign, in contrast Pemphigus Vulgaris is an illn...

anti-desmoglein 3 and 1 autoantibodies are involved in the pathogenesis of pemphigus diseases. our objective was to assess the value of elisa in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris. based on clinical presentation and histopathologic confirmation for the diagnosis of the pemphigus, 38 patients took part in the study. sera of the patients were te...

introduction : pemphigus comprises a group of diseases characterized by cutaneous and mucosal blistering. pemphigus vulgaris (pv) is the most common and important variant. recent reports have revealed the relatively high incidence of pv in iran. the onset or aggravation of many human diseases is attributed to oxidative stress and it has been suggested as one of the several factors responsible f...