نتایج جستجو برای: pemphigus area and activity score

تعداد نتایج: 17019497  

2018
Ana Maria Abreu-Velez Wendy Gao Michael S. Howard

Background The majority of the patients affected by a new variant of endemic pemphigus foliaceus in El Bagre, Colombia (El Bagre EPF or pemphigus Abreu-Manu), have experienced vision problems; we have previously reported several ocular abnormalities. Methods Here, we aimed to investigate reactivity to optic nerves in these patients. We utilized bovine, rat and mouse optic nerves, and performe...

2018
Volker Spindler Jens Waschke

Pemphigus is a severe autoimmune-blistering disease of the skin and mucous membranes caused by autoantibodies reducing desmosomal adhesion between epithelial cells. Autoantibodies against the desmosomal cadherins desmogleins (Dsgs) 1 and 3 as well as desmocollin 3 were shown to be pathogenic, whereas the role of other antibodies is unclear. Dsg3 interactions can be directly reduced by specific ...

Journal: :journal of dental research, dental clinics, dental prospects 0
hamid reza abdolsamadi shermin abdollahzadeh pejman bakianian vaziri akram beheshti elnaz shafigh mohammad vahedi

background and aims. pemphigus is a chronic autoimmune and vesiculobollous disease that can affect skin and different mucous membrane surfaces. primary manifestations occur in oral cavity in almost 60% of cases. the purpose of the present study was to evaluate the epidemiology of pemphigus in tehran, iran in a 20-year period. materials and methods. a retrospective study was conducted on the rec...

2014
Marta Sar-Pomian Marta Kurzeja Lidia Rudnicka Malgorzata Olszewska

BACKGROUND Trichoscopy is becoming increasingly popular in diagnosing hair and scalp diseases. Scalp involvement in pemphigus is common. The scalp may be the first or only site of clinical manifestation of the disease. OBJECTIVE The aim of this study was to analyze whether trichoscopy may be useful in aiding differential diagnosis of scalp lesions in patients with pemphigus vulgaris and pemph...

Journal: :Anais brasileiros de dermatologia 2011
Gilson Antonio Pereira Gonçalves Moema Mignac Cumming Brito Adriana Martinelli Salathiel Thais Serraino Ferraz Domingos Alves Ana Maria Ferreira Roselino

BACKGROUND There are two main clinical subsets of pemphigus: pemphigus vulgaris and pemphigus foliaceus. Clinical and epidemiological changes related to both types of pemphigus have been observed in the last years. OBJECTIVES To analyze a 21-year historical case series of pemphigus vulgaris and pemphigus foliaceus in the northeast region of the state of Sao Paulo, where pemphigus foliaceus is...

Journal: :Journal of oral science 2010
Manojkumar S Thorat Arjun Raju Avani R Pradeep

Increasing evidence indicates that systemic conditions are risk factors of periodontitis. Pemphigus is a group of bullous diseases affecting the oral cavity. The aim of this study was to assess the periodontal status of pemphigus vulgaris (PV) patients. The periodontal status of 50 PV patients and 50 healthy subjects was assessed by a single examiner. PV patients were assessed based on the Clin...

Journal: :Acta dermato-venereologica 2012
Satomi Hosoda Masayuki Suzuki Mayumi Komine Satoru Murata Takashi Hashimoto Mamitaro Ohtsuki

Journal Compilation © 2012 Acta Dermato-Venereologica. ISSN 0001-5555 Pemphigus is an autoimmune mucocutaneous bullous disease characterized by auto-antibodies against cell surface antigens of epidermal keratinocytes. Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are the major subtypes. Several other variants have been proposed, including pemphigus erythematosus, pemphigus vegetans, pemp...

Journal: :Journal of the Medical Association of Thailand = Chotmaihet thangphaet 2008
Suthinee Kulkollakarn Penpun Wattanakrai Vasanop Vachiramon Parichart Chalidapongse

OBJECTIVE Pemphigus is an acquired autoimmune blistering skin diseases, of which pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are two major subtypes. A novel commercial enzyme-linked immunosorbent assay (ELISA) against Dsg1 and Dsg3 has been well established for diagnosis and prediction of disease activity in PF and PV. At present, the benefit of anti-Dsg 1 and anti-Dsg 3 IgG by ELISA i...

2014
Marcela Vendruscolo Ambiel Ana Maria Roselino

BACKGROUND Pemphigus foliaceus and pemphigus vulgaris are endemic in the northeastern region of São Paulo State, Brazil. They are treated mainly with systemic corticosteroids, which may provoke osteoporosis; atherosclerosis, higher blood pressure, insulin resistance, glucose intolerance, hyperlipidemia and abdominal obesity. These side effects of corticoids also constitute criteria for the diag...

Bita rohani , Narges Gholizadeh, Shamsolmolouk Najafi, Zohre Bijad,

Introduction: Pemphigus is a relatively rare autoimmune bullous disease involving skin and mucous epithelia. The disease occurs as a result of production of auto-antibodies against inter-cellular epithelia especially cadherin and desmoglein. Interleukin 17 (IL-17) is one of the specific cytokines of T helper. IL-17 plays an important role in delayed type reaction and recruits neutrophils and mo...

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