نتایج جستجو برای: pedunculopontine tegmental nucleus

تعداد نتایج: 114456  

Journal: :Brain : a journal of neurology 2015
Brian Lau Marie-Laure Welter Hayat Belaid Sara Fernandez Vidal Eric Bardinet David Grabli Carine Karachi

The brainstem pedunculopontine nucleus has a likely, although unclear, role in gait control, and is a potential deep brain stimulation target for treating resistant gait disorders. These disorders are a major therapeutic challenge for the ageing population, especially in Parkinson's disease where gait and balance disorders can become resistant to both dopaminergic medication and subthalamic nuc...

2015
Brian Lau Marie-Laure Welter Hayat Belaid Sara Fernandez Vidal Eric Bardinet David Grabli Carine Karachi

The brainstem pedunculopontine nucleus has a likely, although unclear, role in gait control, and is a potential deep brain stimulation target for treating resistant gait disorders. These disorders are a major therapeutic challenge for the ageing population, especially in Parkinson’s disease where gait and balance disorders can become resistant to both dopaminergic medication and subthalamic nuc...

2015
Edgar Garcia-Rill Brennon Luster Susan Mahaffey Veronica Bisagno Francisco J. Urbano

We consider insomnia a disorder of waking rather than a disorder of sleep. This review examines the role of the reticular activating system, especially the pedunculopontine nucleus, in the symptoms of insomnia, mainly representing an overactive waking drive. We determined that high frequency activity during waking and REM sleep is controlled by two different intracellular pathways and channel t...

2015
Brennon Luster Stasia D'Onofrio Francisco Urbano Edgar Garcia-Rill

The pedunculopontine nucleus (PPN) is part of the Reticular Activating System, and active during waking and REM sleep. Previous results showed that all PPN cells plateau at gamma frequencies and intrinsic membrane oscillations in PPN neurons are mediated by high-threshold N- and P/Q-type Ca(2+) channels. The present study was designed to determine whether some PPN cells have only N-, only P/Q-,...

2015
Edgar Garcia-Rill Stasia D’Onofrio Susan Mahaffey Veronica Bisagno Francisco J. Urbano

Schizophrenia is characterized by major sleep/wake disturbances including increased vigilance and arousal, decreased slow wave sleep, and increased REM sleep drive. Other arousal-related symptoms include sensory gating deficits as exemplified by decreased habituation of the blink reflex. There is also dysregulation of gamma band activity, suggestive of disturbances in a host of arousal-related ...

Journal: :Brain and cognition 2002
Warren H Meck Aimee M Benson

The ability of organisms to time and coordinate temporal sequences of events and to select particular aspects of their internal and external environments to which they will attend is vital to the organism's ability to adapt to the world around them. Numerous psychological theories have been proposed that describe how organisms might accomplish such stimulus selection and represent discrete temp...

2010
Susan D. Motts Brett R. Schofield

The midbrain tegmentum is the source of cholinergic innervation of the thalamus and has been associated with arousal and control of the sleep/wake cycle. In general, the innervation arises bilaterally from the pedunculopontine tegmental nucleus (PPT) and the laterodorsal tegmental nucleus (LDT). While this pattern has been observed for many thalamic nuclei, a projection from the LDT to the medi...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید