The main objective of this study was to prepare colon-specific pellets of budesonide, using pectin as film coating. Pellet cores of budesonide were prepared by extrusion / spheronization technique. Pectin, in different ratios was combined with Eudragit RS30D, Eudragit NE30D or Surelease to produce film coating. The dissolution profiles of pectin coated pellets were investigated in pH of 1.2 (2 ...

Abstract The main objective of this study was to prepare colon-specific pellets of budesonide using pectin as film coating.  Pellet cores of budesonide were prepared by extrusion / spheronization technique. Pectin, in different ratios was combined with Eudragit RS30D, Eudragit NE30D or Surelease to produce film coating. The dissolution profiles of pectin coated pellets were investigated in pH o...

Extracts of etiolated pea (Pisum sativum L.) shoots converted soluble pectin from the seedlings to a trichloroacetic acid-insoluble form. This activity coincided with pectinesterase peaks separated from the extracts by gel filtration and ion exchange. The conversion of pectin to the trichloroacetic acid-insoluble form and pectinesterase exhibited identical responses to pH, with activity only ab...

background: pectinases are pectin degrading class of enzymes including polygalacturonase (pg), polymethyl galacturonase (pmg), pectate lyase (pel), and pectin esterase (pe) that are commonly used in processes involving the degradation of plant materials, such as speeding up the extraction of fruit juices.objectives: a highly methylated pectin degrading bacterium from soil covered with fruit was...

the biopolymer-based nanocomplexes are a group of nanocapsules that are used for encapsulation and control delivery of nutraceuticals. they are formed by binding of proteins and polysaccharides. in this study, complex formation between pectin and sodium caseinate was taken place by addition of pectin solutions(0.2, 0.45 and 0.7 % w/v) into the caseinate solutions (0.5, 1 and 1.5 % w/v) and adju...

Microparticles were prepared, using granular starch and pectin, for encapsulation of ascorbic acid. Three types of starch, 50% amylose corn starch, 70% amylose corn starch and type 4 resistant starch (RS4) were used in combination with high methoxyl pectin at selected ratios (2:1, 1:1, and 1:2). Microparticles were prepared by spray drying using a two-fluid nozzle. Particle size distributions w...

sour orange is one of native fruits of iran, which are widely used in the food industry, medicine and cosmetics. sour orange peel is rich source of pectin and generally discarded as waste. in this research, response surface methodology (rsm) with box–behnken design was employed to optimize and to study the effects of the independent variables (temperature, time and ph) on the yield of pectin an...

the main objective of this study was to prepare colon-specific pellets of budesonide, using pectin as film coating. pellet cores of budesonide were prepared by extrusion / spheronization technique. pectin, in different ratios was combined with eudragit rs30d, eudragit ne30d or surelease to produce film coating. the dissolution profiles of pectin coated pellets were investigated in ph of 1.2 (2 ...

Pectin, a plant cell wall polysaccharide, is mainly used in food industries for its gelling and stabilizing properties. In industrial applications, pectin is usually widely extracted from citrus peels, and in some intances, apple pomace is also used. Lime and lemon are the preferred citrus species used in the extraction of pectin, while orange and grapefruit are used less often. In the food ind...

Abstract The main objective of this study was to prepare colon-specific pellets of budesonide using pectin as film coating.  Pellet cores of budesonide were prepared by extrusion / spheronization technique. Pectin, in different ratios was combined with Eudragit RS30D, Eudragit NE30D or Surelease to produce film coating. The dissolution profiles of pectin coated pellets were investigated in pH o...