PURPOSE Retinal vein occlusion (RVO) and diabetic retinopathy (DR) are two major sight-threatening diseases which may lead to neovascular glaucoma (NVG). The aim of this study was to explore the association between platelet parameters and NVG. METHODS A total of 185 subjects were enrolled for the study from January, 2012 to December, 2015 at the Eye-ENT Hospital of Fudan University. Patients ...

BACKGROUND Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive collapse of the upper airway during sleep. Red blood cell distribution width (RDW) increases platelet activation and has been reported as an independent predictor of adverse outcomes in the general population and is believed to be associated with cardiovascular morbidity and mortality. We evaluated RDW, mean plate...

OBJECTIVES Alteration in platelet morphology and functions are associated with pathological processes and increased risk of vascular complications in patients with diabetes. The purpose of the study was to find the correlation between platelet indices with fasting blood glucose, HbA1c and hs-CRP level in pathogenesis of vascular complications in type 2 diabetic patients. METHODOLOGY The study...

BACKGROUND AND AIM Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory diseases. Many serum biomarkers have been studied for diagnosis and monitoring of disease activity in inflammatory bowel diseases (IBD). Platelets play an important role in inflammation. The aim of the present study is to determine whether platelet indices; mean platelet volume (MPV), platelet distribut...

OBJECTIVE To determine the relationship of bone marrow lesions (BMLs) with phenomena such as clinical symptoms, histological subchondral bone damage, and development of osteoarthritis, a reliable and reproducible method to localize and quantify BMLs accurately is indispensable. Therefore, the goal of the current study was to develop and validate a novel semiautomated segmentation method based o...

Abstract Background As is well recognized that inflammation plays a crucial role in the genesis and progression of various cancer. Here we investigate prognostic value novel index: combination neutrophil to lymphocyte ratio platelet distribution width (coNLR-PDW) post-operation patients with resectable hepatocellular carcinoma (HCC). Methods The receiver operating characteristic (ROC) curve was...

The passive dynamic walker (PDW) has an interesting characteristic that it realizes cyclic locomotion without planning joint trajectories. On the other hand, the walking behavior cannot be controlled because it is dominated by the fixed body dynamics. Observing the human cyclic locomotion that is activated by elastic muscles, we adopt a compliant hip joint on PDW, and we propose the ”phasic dyn...

Introduction Rupture of vertebrobasilar plaque with subsequent thrombosis or distal embolization represents the principal pathophysiology of acute atherothrombotic stroke in the posterior circulation [1]. Multicontrast high-resolution MR imaging (HRMRI) has emerged as an effective tool for the assessment of carotid plaque vulnerability because its lipid-rich/necrotic core (LR/NC), intraplaque h...

BACKGROUND The extent of acute aortic dissection (AAD) was correlated with inflammation positively. On the other side, inflammation was negatively correlated with mean platelet volume (MPV), which can reflect platelet (PLT) activation. The aim of this study was to clarify the relationship between the extent of dissection and PLT activation. METHODS Between February 2010 and October 2013, 147 ...

The design and development processes of complex technical systems are important to the competitiveness of enterprises. These processes are characterised by high creativity and strong non-deterministic dynamics spanning different disciplines, relying on cooperation of different organisations. To successfully support these cooperative activities, methods of experience management are needed. This ...