The aim of this study was to investigate whether the interstitial colloid osmotic pressure (COP(i)) of peritoneum is of importance for peritoneal fluid reabsorption during peritoneal dialysis (PD). For testing this hypothesis, a method to isolate interstitial fluid from the peritoneal membrane and to measure the interstitial COP(i) in the normal peritoneum and directly after the initiation of P...

objectives to explore the effect of a selective 10-week corrective exercise with an emphasis on gait training activities (gta) on the number of falls (nofs), fear of falling, functional balance, timed up and go (tug) test among pd patients. background posture instability and unsteady gait disorders in parkinson’s disease (pd) usually contribute to fall-related fractures. fall-related trauma in ...

Transmembrane or membrane-associated protein dysfunction is increasingly recognized as an important mechanism of pathogenesis in Parkinson's disease (PD). Previous genome-wide association studies and their meta-analysis in PD genes have identified several risk foci in transmembrane protein-encoding genes. Herein, we investigated the effect of 4 such PD-associated genetic variants reported in Ca...

During peritoneal dialysis (PD), constant exposure of mesothelial cells to bioincompatible PD solutions results in the denudation of the mesothelial monolayer and impairment of mesothelial cell function. Hyaluronan, a major component of extracellular matrices, is synthesized by mesothelial cells and contributes to remesothelialization, maintenance of cell phenotype, and tissue remodeling and pr...

We analysed single nucleotide polymorphisms in two transmembrane genes (TMEM98 and TMEM132E) in panic disorder (PD) patients and control individuals from the Faroe Islands, Denmark and Germany. The genes encode single-pass membrane proteins and are located within chromosome 17q11.2-q12, a previously reported candidate region for PD. Three single nucleotide polymorphisms (rs887231, rs887230 and ...

BACKGROUND AND OBJECTIVES Encapsulating peritoneal sclerosis (EPS) is a rare but serious and life-threatening complication of peritoneal dialysis (PD). However, the precise pathogenesis remains unclear; in addition, predictors and early diagnostic biomarkers for EPS have not yet to be established. METHODS Eighty-three peritoneal membrane samples taken at catheter removal were examined to iden...

Peritoneal dialysis (PD) is a life-supporting renal replacement therapy used by 10-15% of patients with end-stage renal failure worldwide. The success of long-term PD depends entirely on the longevity and integrity of the peritoneal membrane. The peritoneum is covered by a mesothelial monolayer beneath which is a basement membrane and submesothelial layer that contains collagen, fibroblasts, ad...

Periodontitis leads to the destruction of dental tissue through polymicrobial interactions, inflammation, and increased oxidative stress. The aim this study was measure levels nitrates (NO3−), malondialdehyde (MDA), membranal fluidity (MF) in gingival subjects with or without periodontitis. A total 120 participants from Dentistry School University Guadalajara were investigated. approved by ethi...

Matrix metalloproteases (MMPs) are endopeptidases that regulate diverse biological processes. Synthesized as zymogens, MMPs become active after removal of their prodomains. Much is known about the metalloprotease activity of these enzymes, but noncanonical functions are poorly defined, and functions of the prodomains have been largely ignored. Here we report a novel metalloprotease-independent,...