Brominated flame retardants (BFRs) are anthropogenic compounds that ubiquitous in most manufactured goods. Few legacy BFRs have been recognised as persistent organic pollutants (POPs) and prohibited since the 2000s. However, continue to be used despite growing concerns regarding their toxicity; they often referred novel (nBFRs). While environmental contamination due chlorinated POPs has extensi...

Concentrations of PBDEs and PBBs were measured in matched blood and breast milk samples from 10 UK couples collected in 2011-12. These data are the first measurements in human serum from the UK since the 2004 EU ban on all uses of the penta-and octa-BDE formulations and the 2008 ban on the use of the deca-BDE formulation in some applications. Serum ∑PBDE tri-hepta concentrations ranging from 1....

Toxicosis was induced in pregnant heifers by feeding 25,000 mg/head/day of FireMaster BP-6, a commercial blend of polybrominated biphenyls (PBB). The PBB feeding decreased dry matter intake approximately 50% by 4 days exposure. Emaciated animals became anorexic a few days prior to death at 33 to 66 days. Weight losses of heifers average 80 kg. Other clinical signs observed were dehydration, dia...

Sixty dairy animals were utilized in seven experiments to determine aspects of the distribution and clearance of FireMaster BP-6. Experimental protocols of various studies provided daily exposures from 0.25 to 25,000 mg, exposures for 1 to 202 days, and total study periods from 10 to 1100 days. Necropsy of 28 animals provided information on residue concentrations in 35 tissues, and the excretio...