stem cell therapy can be useful for spinal cord injury (sci). induced pluripotent stem cells (ipscs) are generated by reprogramming mature, fully differentiated cells into a pluripotent state. the ability to generate pluripotent cells from adult somatic cells without the need for an embryo was a major development in stem cell biology. ipscs were established from mouse fibroblasts and demonstrat...

Bone loss after spinal cord injury leads to increased fragility of bone and subsequent risk for low-trauma fractures in the sublesional parts of the body. Although in such injuries upper limbs are normally innervated, bone loss may occur in the upper extremities. The present study was designed to determine the systemic effects of spinal cord injury on the fracture healing of upper limbs in rabb...

background & aim: spinal cord injury (sci) has a very long history, and its cases form a large proportion of patients admitted to trauma centers in iran. studies show that repair after spinal cord injury can be done. in fact, many pharmaceutical agents, such as erythropoietin (epo), are applied to reduce secondary injury following the initial disorder and to maintain the nerve tissue. methods &...

background: health-related quality-of-life (hr-qol) may be affected by various factors including injury-related characteristics among individuals with spinal cord injury (sci). however, the impact of the influence of these variables has not yet been fully described in iranian population. here, we assessed the relationships between injury-related characteristics and hr-qol among iranian people w...

STUDY DESIGN  Retrospective cohort study. OBJECTIVES  To find out: (1) if the energy of trauma (high and low) influence the outcome after cervical spinal cord injury; (2) if time to decompression and degree of injury (complete and incomplete) influence the outcome after high- and low-energy cervical spinal cord injury. METHODS  Twenty-one consecutive patients with low-energy cervical spinal...

STUDY DESIGN A retrospective review was performed to identify patients at risk for secondary neurologic deterioration after complete cervical spinal cord injury. OBJECTIVE To examine the causes of early neurologic deterioration in patients with complete spinal cord injury at a regional spinal cord injury center. SUMMARY OF BACKGROUND DATA After complete spinal cord injury, neurologic deteri...

it was estimated that 3 million people suffered from spinal cord injury. unfortunately up to date, there are not any reliable clinical treatments for spinal cord injury and researches for treatments of sci have focused on medication, surgery, stem cell transplantation, molecular therapy and tissue engineering. also scientists are trying to use a combination of stem cells and nanotechnology scie...

bone loss after spinal cord injury leads to increased fragility of bone and subsequent risk for low-trauma fractures in the sublesional parts of the body . although in such injuries upper limbs are normally innervated, bone loss may occur in the upper extremities. the present study was designed to determine the systemic effects of spinal cord injury on the fracture healing of upper limbs in rab...