Objective(s): High-risk neuroblastoma is a childhood cancer with poorprognosis despite modern multimodality therapy. Internal radiotherapy using131I-metaiodobenzylguanidine (MIBG) is effective for treating the disease even if it isresistant to chemotherapy. The aim of this study is to evaluate the safety and efficacyof 131I-MIBG radiotherapy combined with myeloablative high-dose chemotherapyand...

haemovigilance is a system with standard program to cover the entire transfusion chain, monitor, evaluate and analyse the data to improve patients’ safety. we report the implemented haemovigilance system in hospitals and transfusion reactions (tr) in iran. methods and materials: this was a prospective descriptive study. the national reporting system for transfusion incidents was introduced in j...

background: the safety of rehabilitation centers is of great importance to ensure the well-being of patients. the present study aimed to determine non-structural and functional vulnerability of state rehabilitation centers of tehran city welfare organization in disasters using national standard instruments in 2014. materials and methods: this study has a descriptive and cross-sectional design. ...

Background: Minoxidil is currently an approved treatment for androgenetic alopecia. Topical tretinoin can enhance skin absorption of minoxidil. Objective: This study has been done in order to determine the efficacy and safety of the solution of 0.5% minoxidil+0.05% tretinoin compared to 2% minoxidil in androgenetic alopecia in men. Patients and Methods: In a randomized, double-blind, parallel-g...

Objective: To study the blood pressure, lipid and glycemic effects and safety of Vaccinium arctostaphylos leaf in the hypertensive hyperlipidemic type 2 diabetic patients. Materials and Methods: The patients took 350 mg standardized plant leaf hydro-alcoholic extract capsule (n=50) or placebo capsule (n=50) three times daily alongside conventional drugs for 2 months. At the baseline and endpoin...

Safety cases offer a means for communicating information about the system safety among the system stakeholders. Recently, the requirement for a safety case has been considered by regulators for safety-critical systems. Adopting safety cases is necessarily dependent on the value added for regulatory authorities. In this work, we outline a structured approach for assessing the level of sufficienc...

In many cases, crashes at intersections account for over 50% of all urban road accidents. The need to reduce these crashes has fostered considerable research on the development and evaluation of traffic safety at intersections. This paper introduces a micro-level behavioral method for estimating crash potential at signalized and unsignalized intersections for different traffic characteristics. ...

This paper uses the Panel Study of Income Dynamics to provide some of the first direct evidence that wealth is systematically higher for consumers with predictably greater income uncertainty. However, the apparent pattern of precautionary wealth is not consistent with a standard parameterization of the life cycle model in which consumers are patient enough to begin saving for retirement early i...