Background: The B-cell defect in X-linked agammaglobulinemia (XLA) is caused by mutations in the gene for Bruton's tyrosine kinase (BTK). BTK mutations result in deficient expression of BTK protein in peripheral blood monocytes. Methods: Using the anti-BTK monoclonal antibody (48-2H), a flow cytometric analysis of intra cytoplasmic BTK protein expression in monocytes was performed to identify I...

Surgical suits allocate a large amount of expenses to hospitals; on the other hand, they constitute a huge part of hospital revenues. Patient flow optimization in a surgical suite by omitting or reducing bottlenecks which cause loss of time is one of the key solutions in minimizing the patients’ length of stay[1] (LOS) in the system, lowering the expenses, increasing efficiency, and also enhanc...

Background: Overcrowding is an important problem for outpatient services in healthcare facilities. Patient flow analysis (PFA) is a useful method for identifying inefficiencies in and facilitating patient flow. Objective: PFA was used to estimate patient wait time and determine how different clinical disciplines impact wait times in the studied hospital.<...

A forty two years old woman with a history of bilateral breast augmentation for cosmetic reasons was presented for poor healing of the surgical site. Tissue and periprosthetic fluid were removed from the wound site revealing an atypical lymphoid infiltrate. Subsequently the patient developed axillary lymph adenopathy. Excisional biopsy was performed. Flow cytometry was non-diagnostic. She conti...

Convective weather events cause capacity reduction in the National Airspace System (NAS), and lead to traffic congestion. To mitigate congestion, strategic air traffic flow management plans traffic flows at a long look-ahead time (2-15 hour). Planning at this timeframe is challenging, due to the wide possibility of weather events and requirement for real-time management. To conquer these challe...

Patient choice is not new to the National Health Service (NHS). The nationalisation of hospitals at the founding of the NHS made it possible for a patient to go to any NHS hospital with a referral from a general practitioner (GP). In practice, however, GPs made these decisions on behalf of their patients and, for the majority of the 60-odd years since the inception of the NHS, patient flows to ...

In the coastal shorelines terrestrial organic materials transported by river runoff represent an important material source to the ocean and is estimated that 0.4×1015 g yr−1 organic carbon is discharged to ocean by land flows or rivers (Meybeck, 1982, He et al, 2010). This amount of riverine organic carbon is sufficient to support the entire organic carbon turnover in the ocean (Williams and Dr...