To detect the biological agents, the DNA detection is most usable due to the sensitivity and the selectivity. Although the key technology of DNA detection is real-time polymerase chain reaction (PCR), which uses exponential amplification of PCR and real-time detection of the amplified DNA fragments, the long thermal cycling time has been the problem to apply the rapid detection of pathogenic or...

Microbiome is the community of commensal, symbiotic and pathogenic microorganism that share our human body space. Intestinal microbiota has a defensive role in human health, it is implicated in metabolic and nutritional processes and plays an important role in the pathophysiology of several diseases. In recent years special attention has been paid to investigations targeting the changes of inte...

BACKGROUND Kocuria, established by Stackebrandt et al., previously was classified into Micrococcus. Only two species, K. rosea and K. kristinae are reported to be associated as pathogenic and found with catheter-related bacteremia and acute cholecystitis. CASE PRESENTATION We herein report the first case of brain abscess caused by Kocuria varians, a gram-positive microorganism, in a 52-year-o...

What is a pathogen? Medical textbooks usually define a pathogen as any microorganism that causes disease. However, this widespread definition is problematic on a number of counts [1, 11]. Moreover, a generally accepted definition is not forthcoming among medical microbiologists, immunologists, and physicians. Here it is argued that there is another, and more pressing question to be asked, namel...

Abstract Important natural antimicrobial compounds derived from Vinca minor L. plant contain a wide variety of secondary metabolites which are useful for brain health (increasing blood circulation in the brain, supporting metabolism, preventing memory loss and problems with concentration premature aging cell), externally they play role tissue repair skin lesion healing. The testing activity alc...