نتایج جستجو برای: paternal age
تعداد نتایج: 762716 فیلتر نتایج به سال:
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BACKGROUND Environmental alternations leading to fetal programming of cardiovascular diseases in later life have been attributed to maternal factors. However, animal studies showed that paternal obesity may program cardio-metabolic diseases in the offspring. In the current study we tested the hypothesis that paternal BMI may be associated with fetal growth. METHODS AND RESULTS We analyzed the...
The authors examined the relation of parental age at birth to the risk of prostate cancer among sons with the use of data from the Framingham Study. During 42 years of follow-up (1949-1993), 141 prostate cancer cases occurred in 2,164 men. All but six cases were confirmed by histologic report. The incidence rate of prostate cancer increased from 1.70 per 1,000 person-years among sons in the low...
Parental age has profound consequences for offspring’s phenotype. However, whether patrilineal affects offspring sperm production remains unknown, despite the importance of male reproductive success in species facing post-copulatory sexual selection. Using a longitudinal dataset on ejaculate attributes houbara bustard, we showed that sired by old fathers had different age-dependent trajectories...
BACKGROUND Previous studies have reported the association between advanced paternal age at birth and the risk of autistic-spectrum disorder in offspring, including offspring with intellectual disability. AIMS To test whether an association between advanced paternal age at birth is found in offspring with high-functioning autistic-spectrum disorder (i.e. offspring without intellectual disabili...
OBJECTIVES We sought to estimate the risk for autism associated with maternal and paternal age across successive birth cohorts. METHODS We linked birth records and autism diagnostic records from the California Department of Developmental Services for children born in California between 1992 and 2000 to calculate the risk associated with maternal and paternal age for each birth cohort as well ...
We review the hypotheses concerning the association between the paternal age at childbearing and childhood psychiatric disorders (autism spectrum- and attention deficit/hyperactive disorder) and adult disorders (schizophrenia, bipolar-, obsessive-compulsive-, and major depressive disorder) based on epidemiological studies. Several hypotheses have been proposed to explain the paternal age effect...
We read with interest the study by Teras et al. (1) in which they found a positive association between advanced paternal age and the risk of hematological malignancies at 40 years of age or older among offspring with no siblings but no overall association. The mechanism proposed to explain the subgroup-specific association (1), namely the joint effects of paternal age (through genetic and epige...
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