Immune reconstitution inflammatory syndrome (IRIS) is originally described in association with antiretroviral therapy (ART) for HIV infected patients. IRIS consists of a broad spectrum of inflammatory diseases, such as infectious inflammatory, neoplastic, and autoimmune diseases, that present after starting an effective ART, leading to CD4+ cells increase and plasma HIV-RNA reduction. IRIS refl...

BACKGROUND DRESS is a rare, life threatening syndrome that occurs following exposure to certain medications, most commonly antibiotics and antiepileptics. While sulfonamide antibiotics are frequently implicated as causative agents for DRESS syndrome, furosemide, a nonantibiotic sulfonamide, has not been routinely reported as the causative agent despite its widespread use. CASE REPORT A 63 year ...

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome associated with anticonvulsant drugs is a rare but potentially life-threatening disease that occurs in response to arene oxide producing anticonvulsant such as phenytoin and carbamazepine. There have been many reports of cross reactivity among the anticonvulsants upon first exposure to the offending drugs. However, there has bee...

BACKGROUND In some patterns of cutaneous adverse drug reactions, and depending on the culprit drug, patch testing has been helpful in confirming its cause. Its value in Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) has not been established in a large cohort of patients. OBJECTIVE The aim of the present study is to evaluate the safety and usefulness of patch testing in DRESS. PAT...

OBJECTIVE Cardiac involvement in drug rash with eosinophilia and systemic symptoms (DRESS) syndrome varies considerably between 4% and 21%. Here we present our case and review literatures for its diagnosis and management. An algorithm for diagnosis of cardiac involvement in DRESS syndrome is proposed in this article. DATA SOURCES Data regarding DRESS-associated myocarditis and eosinophilic my...

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a drug-induced, severe multiorgan system reaction whose exact pathogenesis remains unknown. This study aimed at evaluating specific changes in peripheral blood lymphocyte subtypes associated with DRESS during antibiotic treatment. We analyzed six patients with DRESS. A complete blood count and peripheral blood lymphocytes immunoph...

PURPOSE Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is characterized by prolonged clinical symptoms even after the withdrawal of the culprit drug. Different criteria to diagnose DRESS syndrome have been proposed; however, there have been limited studies on prognostic factors. We investigated appropriate criteria for the diagnosis of DRESS syndrome in practice and with...

today, unemployment has become a major problem in national level as well as in yazd province. the presence of high unemployment has caused considerable amount of wastage of active human resources of the society which otherwise could have been used in various prosperous activities. as a result this situation may lead to poverty, corruption, unequal income distribution and other negative conseque...

We introduce pretty clean modules, extending the notion of clean modules by Dress, and show that pretty clean modules are sequentially CohenMacaulay. We also extend a theorem of Dress on shellable simplicial complexes to multicomplexes.

We report two cases of a 52 and 32-year-old males treated with cefotaxime. On day 23 and 28 of the treatment, the patients have manifested a clinical picture of fever, pruriginous skin rash and facial edema. Blood tests showed marked eosinophilia and atypical lymphocytosis for both patients and only hepatic cytolysis in the second patient. Cefotaxime was discontinued and the clinico-biological ...