•Corepressor recruitment is a genome-wide feature of inflammatory enhancers•Corepressors control enhancer-silencer-promoter looping within the Ccl2 TAD•Corepressors antagonize eRNA transcription and CBP-mediated H3K27 acetylation•Ccl2 depletion in ob/ob mice supports function targeting options While role factors coactivators controlling enhancer activity chromatin structure linked to gene expre...

Patient-generated data is increasingly common in chronic disease care management. Smartphone applications and wearable sensors help patients more easily collect health information. However, current commercial tools often do not effectively support patients and providers in collaboration surrounding these data. This paper examines patient expectations and current collaboration practices around p...