after alzheimer's disease, parkinson's disease is the most common nerve-damaging disease. parkinson's is a progressive and chronic disease where cells secrete dopamine-cut black flesh and in the absence of dopamine in the brain destroyed the irregular body movements. man eats the food that causes the formation of the neurotransmitters. tthree neurotransmitters: dopamine, serotoni...

BACKGROUND Wearable sensors (WS) can accurately measure body motion and provide interactive feedback for supporting motor learning. OBJECTIVE This review aims to summarize current evidence for the effectiveness of WS training for improving balance, gait and functional performance. METHODS A systematic literature search was performed in PubMed, Cochrane, Web of Science, and CINAHL. Randomize...

Expiratory muscle strength training (EMST) is efficacious for improving maximum expiratory pressure (MEP), cough function, and swallowing safety in Parkinson disease (PD). However, there are no published reports describing detraining effects following EMST in persons with PD. Moreover, there are no published reports describing detraining effects following any behavioral swallowing intervention....

background: many patients with parkinson diseases are faced with constant attention disorders and evaluation of these disorders in these patients is important. methods : a cross-sectional study was conducted on 80 patients with parkinson disease and 80 healthy iranian people aged 40 to 70. all participants in the two groups of healthy and patients were examined by neurologists and psychiatrists...

Although physiological function of alpha-synuclein is not yet clearly understood, accumulating evidence strongly suggests it plays a crucial role in the pathogenesis of Parkinson disease. Pathologically, alpha-synuclein is a major component of Lewy bodies, which is the pathological hallmark of Parkinson disease. Alpha-synuclein pathology is observed in the brainstem nuclei, including the dorsal...

In this study, the Multi-Layer Perceptron (MLP)with Back-Propagation learning algorithm are used to classify to effective diagnosis Parkinsons disease(PD).It’s a challenging problem for medical community.Typically characterized by tremor, PD occurs due to the loss of dopamine in the brains thalamic region that results in involuntary or oscillatory movement in the body. A feature selection algor...

Exercise is widely recommended for people with Parkinson (PD). Boxing a popular mode of training. However, including individuals less favorable profiles may have negative impact on participation. We performed systematic review to study the patient characteristics that were included in boxing exercise programs research and reflect possible inclusion criteria professionals can use programs. Indic...

Die Parkinson-Krankheit ist nach der Alzheimer-Krankheit die häufigste neurodegenerative Erkrankung. Sie wird zur Gruppe hypokinetischen Bewegungsstörungen gezählt. Atypische Parkinson-Syndrome stellen eine pathologisch inhomogene seltener neurodegenerativer Erkrankungen dar, im Vergleich durch einen maligneren Verlauf und ein schlechteres Therapieansprechen gekennzeichnet sind. Neuroprotektive...

Penyakit Parkinson adalah penyakit yang prevalensinya terus meningkat seiring peningkatan usia harapan hidup. Penemuan obat baru memiliki aktivitas lebih kuat dengan resiko efek samping rendah masih menjadi tantangan tersendiri. Senyawa turunan 4-(3-nitrophenyl)-thiazol-2-ylhydrazone diketahui aktif sebagai inhibitor monoamin oxidase B (MAO-B). MAO-B merupakan target kerja penting dalam pengoba...