نتایج جستجو برای: parallel mechanisms pm
تعداد نتایج: 781280 فیلتر نتایج به سال:
In the title complex, [RuCl2(C12H9BrN2)2] or [RuCl2(PM-BrA)2] (PM-BrA = 4-bromo-N-(2'-pyridyl-methyl-ene)aniline), the Ru(II) cation is located on a centre of inversion and is surrounded by four N atoms of two PM-BrA ligands in the equatorial plane and by two Cl atoms in a trans axial arrangement, displaying a distorted octa-hedral coordination environment. Two C atoms in the benzene ring of th...
OBJECTIVES The specific objectives are threefold: to describe the biologically plausible mechanistic pathways by which exposure to particulate matter (PM) may lead to the adverse perinatal outcomes of low birth weight (LBW), intrauterine growth retardation (IUGR), and preterm delivery (PTD); review the evidence showing that nutrition affects the biologic pathways; and explain the mechanisms by ...
Block iterative methods are applied to hydrodynamic simulations of a one-dimensional (1-D) submicrometer semiconductor device. We show that block successive underrelaxation (SUR) converges with a fixed relaxation factor w = 0.13 for simulations at 300 K and w = 0.04 at 77 K . To demonstrate the robustness of the block iterative method, we present numerical simulations of a steady-state electron...
Metabolic networks link cellular phenotypes to the corresponding genotypes. Large-scale structural analysis of metabolic networks is now focusing on the mechanisms underlying robustness in structural networks. Our primary goal is to analyze the mechanisms of metabolic networks using Phenotype Microarray (PM) data. We developed a computational model of central metabolism in Escherichia coli unde...
Refinement is a fundamental design technique that has often challenged the “formal methods” community. In most cases, mathematical elegance and proof manageability have been chosen over flexibility and freedom, which are often needed in practice to deal with unexpected or critical situations. The issue of refinement becomes even more critical when dealing with real-time systems where time analy...
Air pollution is a major challenge to public health. Ambient fine particulate matter (PM) is the key component for air pollution, and associated with significant mortality. The majority of the mortality following PM exposure is related to cardiovascular diseases. However, the mechanisms for the adverse effects of PM exposure on cardiovascular system remain largely unknown and under active inves...
RATIONALE Acute and chronic exposures to airborne particulate matter (PM) have been linked in epidemiological studies to a wide spectrum of cardiovascular disorders that are characterized by a dysfunctional endothelium. The pathophysiological mechanisms underlying these associations are unclear. OBJECTIVE To examine whether exposure to fine PM with an aerodynamic diameter of <2.5 microm (PM(2...
Airborne particulate matter (PM) increases morbidity and mortality resulting from cardiopulmonary diseases including cancer. We hypothesized that PM is genotoxic to alveolar epithelial cells (AEC) by causing DNA damage and apoptosis. PM caused dose-dependent AEC DNA strand break formation, reductions in mitochondrial membrane potential (Delta psi m), caspase 9 activation, and apoptosis. An iron...
In 1998 Congress mandated expanded U.S. Environmental Protection Agency (U.S. EPA) health effects research on ambient air particulate matter (PM) and a National Research Council (NRC) committee to provide research oversight. The U.S. EPA currently supports intramural and extramural PM research, including five academically based PM centers. The PM centers in their first 2.5 years have initiated ...
Prospective memory (PM) is the ability to remember to accomplish an action when a particular event occurs (i.e., event-based PM), or at a specific time (i.e., time-based PM) while performing an ongoing activity. Strategic Monitoring is one of the basic cognitive functions supporting PM tasks, and involves two mechanisms: a retrieval mode, which consists of maintaining active the intention in me...
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