Cosmetic preparations contain a large number of ingredients. Some them may have negative consequences, most often in the form allergic reactions, skin irritations, hormonal disorders, increased risk cancer. These chemicals are added to protect, soften, or otherwise make product more usable. The aim this study was determine presence some potentialy harmful substances by qualitative analysis cosm...

In the automation of sample dilution or derivatization, the performance of the mixing technique employed when adding solvents or reagents to samples is critical. This paper presents a newly developed mixing method, based on conventional aspiration and dispensing of liquid techniques, but which considerably improves the precision of mixing. The paper discusses the results of a comparison of the ...

Diffusion coefficients (D) of parabens and steroids in water and 1-octanol were determined by using the chromatographic broadening method at 37 degrees C, and the relationships between the D values and the physicochemical properties of the drugs were discussed. The D values in 1-octanol were lower than those in water because of the higher viscosity of 1-octanol. The D values depend on not only ...

The link between exposure to endocrine disrupting chemicals (EDCs) and the rapid increase in prevalence of obesity has recently been suggested. However, magnitude health impact EDC at-risk populations remain largely unclear. In this study, we investigated effect a dietary intervention driven reduction adipose tissue on urinary mobilization, whether higher leads impaired weight loss obese indivi...

Non-persistent endocrine disrupting chemicals (npEDCs) can affect multiple organs and systems in the body. Whether npEDCs can accumulate in the human brain is largely unknown. The major aim of this pilot study was to examine the presence of environmental phenols and parabens in two distinct brain regions: the hypothalamus and white-matter tissue. In addition, a potential association between the...

BACKGROUND Human exposure to parabens and other antimicrobial chemicals is continual and pervasive. The hormone-disrupting properties of these environmental chemicals may adversely affect human reproduction. OBJECTIVE We aimed to prospectively assess couples' urinary concentrations of antimicrobial chemicals in the context of fecundity, measured as time to pregnancy (TTP). METHODS In a pros...

Preservatives are chemical substances whose role is to protect medicinal products against harmful changes caused by microorganisms. They are added to sterile medicinal products, such as eye drops and multidose solutions for injections, as well as to non-sterile products, such as water oral solutions, creams, gels, suppositories and capsules with liquid content. The most commonly used preservati...