Chronically ill patients with neurodegenerative and neurobehavioural and psychiatric diseases commonly have systemic and central nervous system bacterial and viral infections. In addition, other chronic illnesses where neurological manifestations are routinely found, such as fatiguing and autoimmune diseases, Lyme disease and Gulf War illnesses, also show systemic bacterial and viral infections...

Case presentation: Male, 10 years old, referred to psychiatric care due aggressiveness, stereotyped movements, progressively started 6 months ago, related an outbreak of COVID-19 in the family - patient did not show symptoms. At consultation, mother reported that performed “twitching,” opisthotonic, oculogyric crises, and vocal intonations, addition obsessive movements relieve thoughts somethin...

There is a pressing need to reduce the high global disease burden of rheumatic heart disease (RHD) and its harbinger, acute rheumatic fever (ARF). ARF is a classical example of an autoimmune syndrome and is of particular immunological interest because it follows a known antecedent infection with group A streptococcus (GAS). However, the poorly understood immunopathology of these post-infectious...