To identify and characterize genes, the products of which play a role in pancreatic adenocarcinoma, we constructed a complementary DNA (cDNA) library using inKN \ from the pancreatic adenocarcinoma cell line 111'\ I . grown as a nude mouse tumor. Through differential screening, we identified a cDNA clone, pIISB, that is homologous to an mRNA expressed at significantly higher levels in HPAF cell...

OBJECTIVE Resective therapeutic strategy for left-sided pancreatic adenocarcinoma is open to debate. The post-resection outcomes and factors influencing post-resection survival for adenocarcinoma of the body and tail of the pancreas were analyzed to determine the effectiveness of surgery. METHODS A total of 73 patients with adenocarcinoma of the body or tail of the pancreas who underwent rese...

To the Editor: Cystic neoplasms of the pancreas are rare, constituting only 10% of all cystic lesions of the pancreas in the adult population. These neoplastic pancreatic cysts can be divided into serous adenomas, mucinous cystadenomas, and cystadenocarcinomas. Acinar cell cystadenocarcinomas (ACCCs) are a very rare variant of acinar cell adenocarcinoma of the pancreas, of which only 7 cases ha...

A case of invasive ductal carcinoma of an ectopic pancreas in the stomach in a 74-year-old woman is presented. A 4.0 cm gastric submucosal tumor (SMT) was resected surgically. Histologically, the tumor showed cystic tissue consisting of an ectopic pancreas with foci of a moderately differentiated tubular adenocarcinoma. In this tumor, small pancreatic tissues, acini, Langerhans islets, and duct...

Presenter: Fabio Makdissi MD | Sírio Libanês Hospital Background: Pancreatoduodenectomy is the procedure of choice for resectable tumors located in head pancreas. Invasion major vessels, particularly portal and superior mesenteric vein a relative contraindication minimally invasive approach. We present video robotic resection reconstruction without use graft during pancreatoduodenectomy. Method...

The delivery of postoperative combined modality adjuvant therapy for completely resected pancreatic cancer was initially shown to be beneficial on the basis of a prospective, randomized trial published in 1985. Since then, oncologists have debated whether chemotherapy, chemoradiation, or both is optimal adjuvant therapy after pancreatectomy for ductal adenocarcinoma of the pancreas; no global c...

Introduction The association of neurofibromatosis with malignant tumours of the neural crest is well documented. Neurofibromatosis may also be associated with other malignant tumours such as carcinoid of the ampulla of Vater (Barber, 1976), adenocarcinoma of the pancreas (Kellar and Logan, 1977), adenocarcinoma of the colon (Jenkins and Gill, 1972), Wilms' tumour (Stay and Vauter, 1977), rhabdo...

Primary signet cell carcinoma of the prostate is a rare histological variant of prostate malignancies. It is commonly originated from the stomach, colon, pancreas, and less commonly in the bladder. Prognosis of the classical type is worse than the adenocarcinoma of the prostate. Primary signet cell adenocarcinoma is diagnosed by eliminating the adenocarcinomas of other organs such as gastrointe...

CONTEXT Squamous cell carcinoma of the pancreas is an unusual tumor due to the absence of squamous cells in the normal pancreas. Its clinical presentation is similar to that of adenocarcinoma of the pancreas and is usually diagnosed intraoperatively or at autopsy. CASE REPORT We report a 50-year-old male who presented with obstructive jaundice and symptoms suggestive of gastric outlet obstruc...

Pancreaticoduodenectomy is performed on carefully selected patients as part of a protocol-based clinical research program emphasizing the importance of multimodality management for patients with potentially resectable adenocarcinoma of the pancreatic head. Treatment schemas emphasize the importance of minimizing toxicity and treatment duration, while attempting to improve therapeutic efficacy. ...