Pachyonychia congenita (PC) is a rare skin disease that inherited in an autosomal dominant pattern. PC associated with mutations the genes encoding keratins K6, K16 or K17, which are related to epidermal hyperproliferation. patients experience severe and painful palmoplantar keratoderma accompanied by blistering highly disabling as it greatly impairs ambulation. No curative treatment currently ...

Background Numerous therapeutic modalities have been proposed to treat the manifestations of pachyonychia congenita (PC). While research hopes lie with molecular therapies, patients are in need of answers regarding the efficacy of conventional treatments. Aim of the study To determine patients’ experience and preferences regarding conventional treatments for PC. Methods The study population inc...