Abstract Hidradenitis suppurativa (HS) is a difficult-to-treat, painful, chronic inflammatory skin disorder characterized by nodules, abscesses and tunnels. Delay in diagnosis increases disease severity overall burden. In England, HS associated with high healthcare resource use, an estimated prevalence of 1.2% the general UK population (Ingram JR, Jenkins-Jones S, Knipe DW et al. Population-bas...

A semi-Markov HMM (more properly called a hidden semi-Markov model, or HSMM) is like an HMM except each state can emit a sequence of observations. Let Y (Gt) be the subsequence emitted by “generalized state” Gt. The “generalized state” usually contains both the automaton state, Qt, and the length (duration) of the segment, Lt. We will define Y (Gt) to be the subsequence yt−l+1:t. After emitting...

We have read with great interest the two editorials by Burdorf et al: “The COVID-19 pandemic: one year later – an occupational perspective” (1) and (Coronavirus) consequences for health” (2). The authors highlight importance of societal outbreak changes in world work to manage health. key points identified such as individual socio­economic factors, psychological effects occupations highest risk...

SUBMISSIONS First AuthorCo-AuthorsTITLENo.G. DedieuA. KarnieliO. HagolleH. JeanjeanF. CabotP. FerrierY. YanivTHE VENμS MISSION: EARTHOBSERVATION WITH HIGH SPATIALAND TEMPORAL RESOLUTIONCAPABILITIEST4 A. LyapustinY. WangA GENERIC AEROSOL-SURFACEREFLECTANCE RETRIEVALALGORITHM FOR MODIST5 C. BorelC. SpencerATMO...

Creep damage is one of the serious problems for the high temperature industries and computational approach (such as continuum damage mechanics) has been developed and used, complementary to the experimental approach, to assist safe operation. However, there are no ready creep damage constitutive equations to be used for predicting the lifetime for this type of alloy, particularly for low stress...

In the past 20 years, AI researchers in knowledge representation (KR) have implemented over 50 frame knowledge representation systems (FRSs). KR researchers have explored a large space of alternative FRS designs. This paper surveys the FRS design space in search of design principles for FRSs. The FRS design space is de ned by the set of alternative features and capabilities | such as the repres...

We use evidence from the Second Reform Act, introduced in the United Kingdom in 1867, to analyze the impact on electoral outcomes of extending the vote to the unskilled urban population. Exploiting the sharp change in the electorate caused by franchise extension, we separate the effect of reform from that of underlying constituency level traits correlated with the voting population. Although we...