Leadership generally entails sustaining, improving, or changing strategic directions within small or large, simple or complex, organizations. 1 Today’s era raises issues for leadership that focus on reducing social and health benefits, and downsizing workforces and related services. Leadership requires making choices with finite resources based upon plausible alternatives, and it depends on mot...

Organizations generally are not responding effectively to rising IT security threats because people issues receive inadequate attention. The stark example of IT security is just the latest strategic IT priority demonstrating deficient IT leadership attention to the social dimension of IT. Universities in particular, with their devolved people organization, diverse adoption of IT, and split cent...

For over a half century, leadership researchers have attempted to identify the aspects of leadership that improve organizational performance, yet the answer is still elusive. In this commentary, we discuss several reasons for the slow progress. There is a lack of collaborative effort between academics and practitioners, and the leadership theory and research has lacked adequate emphasis on stra...

In our long-term research we have created a new management and leadership methodology, which can be used for strategic management purposes to manage change and to lead the company resources efficiently and effectively towards the new future. Our research methods are based on management and leadership ontologies, with which we can capture the current and future views of personnel for use in stra...

Case-based research was conducted on strategy and IT evolution in the Boeing Company. Results showed IT investment in the 20th century supported an increasingly decentralized hierarchical functional corporate organization structure, and shifted during the early decades of the 21st century toward an IT-enabled global network organization structure. IT investment context changed from an inward fo...

Quantification of the peripheral nerve myelin glycoprotein P0 and antibodies to P0 is difficult due to insolubility of P0 in physiological solutions. We have overcome this problem by using the water-soluble recombinant form of the extracellular domain of P0 (P0-ED) and describe newly developed assays which allow detection and quantitation of P0 and antibodies to P0, in serum and cerebrospinal f...