For p > 0, let B(Bn) and Lp(Bn) respectively denote the p-Bloch and holomorphic p-Lipschitz spaces of the open unit ball Bn in C . It is known that B(Bn) and L1−p(Bn) are equal as sets when p ∈ (0, 1). We prove that these spaces are additionally norm-equivalent, thus extending known results for n = 1 and the polydisk. As an application, we generalize work by Madigan on the disk by investigating...

The Legionella pneumophila dotA gene is required for intracellular growth of the bacterium in macrophages. In this study, a structure-function analysis of the DotA protein was conducted to elucidate the role of this protein in L. pneumophila pathogenesis. Translational fusions of dotA to the Escherichia coli phoA and lacZ genes indicated that DotA is an integral cytoplasmic membrane protein wit...

Abstract Chung, Diaconis, and Graham considered random processes of the form Xn+1 = 2Xn + bn (mod p) where X0 = 0, p is odd, and bn for n = 0, 1, 2, . . . are i.i.d. random variables on {−1, 0, 1}. If Pr(bn = −1) = Pr(bn = 1) = β and Pr(bn = 0) = 1− 2β, they asked which value of β makes Xn get close to uniformly distributed on the integers mod p the slowest. In this paper, we extend the results...

For n ≥ 2, let Bn denote the unit ball in R, and for p ≥ 1 let L denote the Banach space of p-summable functions on Bn. Let L p h(Bn) denote the subspace of harmonic functions on Bn that are p-summable. When n = 2, we often write D instead of B2, and we let A denote the Bergman space of analytic functions in L. Let ω be a function in L. We are interested in finding the best approximation to ω i...

The purposes of this study were to develop an efficient method of labeling D-glucosamine hydrochloride with gallium 68 (68Ga) and investigate the imaging properties of the resulting radiotracer in a human tumor xenograft model using micro-positron emission tomography (μPET). The precursor compound 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)-2-deoxy-D-glucosamine (DOTA-DG) wa...

Dioctatin A (DotA), a metabolite of Streptomyces, is known to be an inhibitor of human dipeptidyl aminopeptidase II. Here, it was found that DotA strongly inhibited aflatoxin production by Aspergillus parasiticus, with an IC50 value of 4.0 microM. The mycelial growth of the fungus was not affected by the addition of DotA at a concentration of 50 microM, but inhibition of conidiation was observe...

The aim of this study was to observe and compare the endogenous circadian rhythm and photoresponse of Clock gene transcription in the suprachiasmatic nucleus (SCN) and pineal gland (PG) of rats. With free access to food and water in special darkrooms, Sprague-Dawley rats were housed under the light regime of constant darkness (DD) for 8 weeks (n=36) or 12 hour-light: 12 hour-dark cycle (LD) for...

The objective of this study was to determine a classification system for BN in incarcerated groin hernia patients and to explore the possible relationship between BN staging and patient outcomes. Incarcerated groin hernia patients treated with emergency bowel resection from January 2008 to December 2013 were screened for inclusion in a prospective study. A novel three-stage classification syste...

Numerous intracellular bacterial pathogens modulate the nature of the membrane-bound compartment in which they reside, although little is known about the molecular basis for this control. Legionella pneumophila is a bacterial pathogen able to grow within human alveolar macrophages and residing in a phagosome that does not fuse with lysosomes. This study demonstrates that the dotA product is req...

Bestrophins have recently been proposed to comprise a new family of Cl(-) channels. Our goal was to test whether mouse bestrophin-2 (mBest2) is a bona fide Cl(-) channel. We expressed mBest2 in three different mammalian cell lines. mBest2 was trafficked to the plasma membrane as shown by biotinylation and immunoprecipitation, and induced a Ca(2+)-activated Cl(-) current in all three cell lines ...