نتایج جستجو برای: oxytocin tgf

تعداد نتایج: 35984  

Journal: :Brain research 2003
Shuang Quan Yu Thomas Lundeberg Long Chuan Yu

The present study was conducted on rats with inflammation induced by subcutaneous injection of carrageenan into the left hindpaw. Intrathecal administration of oxytocin produced dose-dependent increases in the hindpaw withdrawal latency (HWL) to thermal and mechanical stimulation in rats with inflammation. The antinociceptive effect of oxytocin was blocked by intrathecal administration of atosi...

Journal: :iranian journal of applied animal science 2015
m. nezamidoust s. razzaghzadeh e. ezati r. ghorbani

determination of milk yield potential using an accurate method is essential for assessing nutritional requirements, evaluation of genetic potential, lamb growth and survival, management decisions and improving performance traits of sheep flocks. exogenous oxytocin injection is applied to estimate milk secretion rate in sheep. oxytocin is a neurohormone produced in the hypothalamo-neurohypophysi...

Journal: :acta medica iranica 0
zh. abedi asl m. farrokhi m. rajaee

the purpose of this study was to compare the efficacy and safety of misoprostol and oxytocin for induction of labor. in this prospective and randomized controlled trial one hundred twenty women with an unfavorable cervix who underwent labor induction were assigned to receive either intravenous high dose oxytocin(6miu/min) or intravaginal misoprostol 50µg every 6 hours for two doses. twelve hour...

Journal: :The international journal of neuropsychopharmacology 2014
Rebecca Clark-Elford Pradeep J Nathan Bonnie Auyeung Valerie Voon Akeem Sule Ulrich Müller Robert Dudas Barbara J Sahakian K Luan Phan Simon Baron-Cohen

It has been hypothesised that the mechanisms modulating social affiliation are regulated by reward circuitry. Oxytocin, previously shown to support affiliative behaviour and the processing of socio-emotional stimuli, is expressed in areas of the brain involved in reward and motivation. However, limited data are available that test if oxytocin is directly involved in reward learning, or whether ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه گیلان - دانشکده علوم پایه 1389

مایع آمنیوتیک (af) برای سلامت جنین حائز اهمیت است زیرا یک کیسه حمایت کننده گرداگرد جنین تشکیل میدهد که حاوی مواد مغذی و فاکتورهای رشد می باشد.اهمیت فاکتورهای رشد در رشد طبیعی جنین به اثبات رسیده است. در مایع آمنیوتیک انسان فاکتور رشد ترانس فرم کننده بتا-1 (tgf-?1) وجود دارد وتصور میشود که در هنگام تکوین معده و لوله های تنفسی عمل کند . tgf-beta یک سایتوکین چندکاره است که در تنظیم تمایز، تشکیل ما...

Journal: :European journal of endocrinology 1997
J J Evans

Those of us who study physiology are tempted to hope that the experimental perturbations which we induce affect only the organ which has ensnared our interest. This review uses physiological systems which incorporate oxytocin as models to indicate some of the ways in which departure from such investigative paradise occurs, and also to discuss some of the implications of a physiology which uses ...

2016
H Kosaka Y Okamoto T Munesue H Yamasue K Inohara T Fujioka T Anme M Orisaka M Ishitobi M Jung T X Fujisawa S Tanaka S Arai M Asano D N Saito N Sadato A Tomoda M Omori M Sato H Okazawa H Higashida Y Wada

Recent studies have suggested that long-term oxytocin administration can alleviate the symptoms of autism spectrum disorder (ASD); however, factors influencing its efficacy are still unclear. We conducted a single-center phase 2, pilot, randomized, double-blind, placebo-controlled, parallel-group, clinical trial in young adults with high-functioning ASD, to determine whether oxytocin dosage and...

Journal: :Journal of reproduction and fertility 1983
A P Flint E L Sheldrick

Jugular venous concentrations of oxytocin and progesterone changed in parallel during the oestrous cycle in the ewe, falling at luteal regression and rising with formation of the new corpus luteum. These fluctuations in the circulating concentration of oxytocin were not caused by changes in its metabolic clearance rate. On Days 6-9 of the cycle circulating oxytocin concentrations exhibited a di...

2011
Michel Mazzuca Marat Minlebaev Anastasia Shakirzyanova Roman Tyzio Giuliano Taccola Sona Janackova Svetlana Gataullina Yehezkel Ben-Ari Rashid Giniatullin Rustem Khazipov

The mechanisms controlling pain in newborns during delivery are poorly understood. We explored the hypothesis that oxytocin, an essential hormone for labor and a powerful neuromodulator, exerts analgesic actions on newborns during delivery. Using a thermal tail-flick assay, we report that pain sensitivity is two-fold lower in rat pups immediately after birth than 2 days later. Oxytocin receptor...

2013
M Yamashita Y Takayanagi M Yoshida K Nishimori M Kusama T Onaka

Food intake activates neurones expressing prolactin-releasing peptide (PrRP) in the medulla oblongata and oxytocin neurones in the hypothalamus. Both PrRP and oxytocin have been shown to have an anorexic action. In the present study, we investigated whether the activation of oxytocin neurones following food intake is mediated by PrRP. We first examined the expression of PrRP receptors (also kno...

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