BACKGROUND Perioperative optimization of spatially resolved near-infrared spectroscopy determined cerebral frontal lobe oxygenation (scO2) may reduce postoperative morbidity. Norepinephrine is routinely administered to maintain cerebral perfusion pressure and, thereby, cerebral blood flow, but norepinephrine reduces the scO2. We hypothesized that norepinephrine-induced reduction in scO2 is infl...

Myocardial mean myoglobin oxygen saturation was determined spectroscopically from isolated guinea pig hearts perfused with red blood cells during increasing hypoxia. These experiments were undertaken to compare intracellular myoglobin oxygen saturation in isolated hearts perfused with a modest concentration of red blood cells (5% hematocrit) with intracellular myoglobin saturation previously re...

Pulse oximetry is a useful way to monitor oxygen saturation in patients in a variety of clinical settings. Nurses need to understand the principles of oxygen transport and delivery to use pulse oximetry effectively in clinical practice.

We report a case of rheumatic heart disease with severe mitral stenosis having cyanosis and low oxygen saturation on pulse oximetry. The findings of clinical examination and low values on pulse oximetry were inconsistent with the findings of normal partial pressure of oxygen and oxygen saturation on arterial blood gas analysis, leading to diagnostic dilemma. In such clinical scenario, the anest...

PURPOSE To determine the retinal oxygen saturation trend with onset of diabetes and increasing severity of diabetic retinopathy by comparing diabetic groups with and without retinopathy to controls. METHODS A fundus camera-based dual-wavelength snapshot oximeter imaged retinas of healthy subjects and patients with and without diabetic retinopathy. The images were analyzed to determine oxygen ...

We have evaluated three different devices for oxygen administration in the surgical ward, the Hudson face mask (oxygen 3 litre min-1, air 12 litre min-1), the nasal prong (oxygen 3 litre min-1) and the binasal catheter (oxygen 3 litre min-1). We evaluated the three devices in random order for periods of 30 min each in 25 patients with postoperative hypoxaemia (SpO2 < or = 94%). Arterial oxygen ...

OBJECTIVE To reduce hyperoxia in very low birth weight infants who receive supplemental oxygen, the Children's Mercy Hospital neonatal respiratory quality improvement committee introduced the potentially better practice of oxygen saturation targeting and identified strategies to overcome barriers to implementation of this practice. METHODS Using rapid-cycle quality improvement projects, this ...

background : due to the higher risk of  pain in preterm infants, pain management is important for such infants. the present study aimed to determine the effectiveness of kangaroo care on the severity of pain and physiological parameters after heel-stick in preterm infants. materials and methods: this was a prospective and randomized controlled cross-over study. twenty preterm infants allocated ...

BACKGROUND Perioperative disturbances of microvascular blood flow and oxygenation in the intestinal tract have been hypothesized to play an important role in development of the multiple organ dysfunction syndrome. Herein, increased intra-abdominal pressure (IAP) has been identified as a key factor in the initiation of the pathophysiologic cascade. The authors hypothesized that increasing the IA...