Oxidative damage has been proposed as one of the possible mechanism involved in the nephrotic syndrome. Strengthening the defense system by antioxidants may provide protection against oxidative damage. Therefore, this study was carried out to investigate oxidant and antioxidant status with copper, zinc and homocysteine in nephrotic syndrome patients and the effect of antioxidants, minerals and ...

Oxidative stress could trigger lipid accumulation in liver and thus hepatic steatosis. Tea is able to prevent liver disorders, but a direct link between antioxidant capacities and prevention of steatosis has not been reported yet. We aimed to investigate such relationship in a rat model of high fat-high sucrose diet (HFS)-induced obesity and to explore more deeply the mechanisms in isolated hep...

INTRODUCTION To investigate the oxidative stress and its association with antioxidants in patients on hemodialysis, we evaluated the levels of albumin, C-reactive protein (CRP), ferritin, vitamin E, glutathione, and total antioxidant capacity in these patients. MATERIALS AND METHODS In a cross-sectional study, we enrolled 25 patients on maintenance hemodialysis and measured the inflammatory a...

The concepts of oxidative stress and antioxidants have been implicated in neurodegenerative disorders. Oxidative stress was assessed by estimating lipid peroxidation product in the form of thiobarbituric acid reactive substances (TBARS). Enzymatic antioxidants like superoxide dismutase(SOD), glutathione peroxidase(GPx), catalase, ceruloplasmin and non enzymatic antioxidant vitamins like vitamin...

Exercise training may increase production of free radicals and reactive oxygen species in different ways. The training type and intensity may influence free radicals production, which leads to differences in oxidative stress status between athletes, but the results of the previous studies are incosistent. The aim of our study was to estimate oxidative stress status in elite athletes engaged in ...

A complex antioxidant system has been developed in mammals to relieve oxidative stress. However, excessive reactive species derived from oxygen and nitrogen may still lead to oxidative damage to tissue and organs. Oxidative stress has been considered as a conjoint pathological mechanism, and it contributes to initiation and progression of liver injury. A lot of risk factors, including alcohol, ...

Experimental studies have demonstrated that oxidative stress plays an essential role in the pathophysiology of ischemic stroke. The objective of the present study was to assess some serum markers of oxidative stress in patients in the early period of ischemic stroke and determine whether vitamin C supplementation affects the parameters of oxidative stress and the clinical status of patients. Th...

Experimental studies have demonstrated that oxidative stress plays an essential role in the pathophysiology of ischemic stroke. The objective of the present study was to assess some serum markers of oxidative stress in patients in the early period of ischemic stroke and determine whether vitamin C supplementation affects the parameters of oxidative stress and the clinical status of patients. Th...