objective: oxidative stress that damages proteins result in aging and age related diseases. the aim of this study is to determine the effect of tocotrienol rich fraction (trf) on the expression of proteins in oxidative stress-induced caenohabditis elegans (c.elegans) which has homologous genes to humans. methods: the worms were treated with trf prior to, after and continuously in separate group...

background: the present study describes the susceptibility of prepubertal testis of mice to prooxidant induced oxidative impairments both under in vitro and in vivo exposure conditions. materials and methods: following in vitro exposure to iron (5,10 and 25 m), oxidative response measured in terms of lipid peroxidation and hydroperoxide levels in testis of pre pubertal mice (4 wk) was more robu...

background: this study investigated the protective effects of aqueous extracts of anogeissus leiocarpus (dc) guill & perr (combretaceae) and terminalia avicennioides guill & perr (combretaceae) root barks, as well as their 1:1 (w/w) mixture on liver redox and haematological parameters of diethylnitrosamine-treated rats. methods: rats were orally administered distilled water, diethylnitrosamine ...

introduction: the role of ovarian hormones and nitric oxide (no) on oxidative damage in brain tissues as well as learning and memory has been widely investigated.the present study was carried out to evaluate the effect of the precursor of no, l-arginine on learning and brain damage due to oxidative stress in ovariectomized (ovx) rats.methods: thirty -two rats were divided into four groups: 1) s...

background: diabetes is one of the most common metabolic disorders and is related to oxidative-stress-induced diseases. given the role of dietary antioxidants in the control and prevention of diabetes, this study aimed to examine the effects of sesame butter versus sesame oil on the serum levels of glucose, lipid profile, and oxidative stress biomarkers in diabetic rats. methods: forty male alb...

conclusions beta-alanine supplementation has limited antioxidant effect during the repeated wts. background carnosine is a dipeptide formed from the β-alanine and histidine amino acids and found in mainly in the brain and muscle, especially fast twitch muscle. carnosine and creatine has an antioxidant effect and carnosine accounts for about 10% of the muscle's ability to buffer the h+ ions prod...

objective(s): oxidative stress has been established as a key cause of alcohol-induced hepatotoxicity. licochalcone b, an extract of licorice root, has shown antioxidative properties. this study was to investigate the effects and mechanisms of licochalcone b in ethanol-induced hepatic injury in an in vitro study. materials and methods: an in vitro model of ethanol-induced cytotoxicity in brl cel...

introduction: this study aimed to evaluate the effect of short-term creatine supplementation on oxidative stress and antioxidant enzymes after six bouts of 50-meter sprint swimming. methods: this quasi-experimental study recruited eight trained female swimmers with the mean age of 25±4.4 years and body mass index (bmi) of 21.8±4.2 kg/m2 to perform six bouts of 50-meter sprint swimming with a 12...

objective(s): hyperglycemia, oxidative stress and apoptosis have key roles in pathogenesis of diabetic neuropathy. there are local renin-angiotensin systems (rass) in different tissues such as neural tissue. local rass are involved in physiological and pathophysiological processes such as inflammation, proliferation and apoptosis. this study aimed to investigate the role of local renin-angioten...