Ras and Rho GTPases are molecular switches for various vital cellular signaling pathways. Overactivation of these GTPases often causes development of cancer. Guanine nucleotide exchange factors (GEFs) and oxidants function to upregulate these GTPases through facilitation of guanine nucleotide exchange (GNE) of these GTPases. However, the effect of oxidants on GEF functions, or vice versa, has n...

Pseudomonas aeruginosa ohrR and ospR are gene homologs encoding oxidant sensing transcription regulators. OspR is known to regulate gpx, encoding a glutathione peroxidase, while OhrR regulates the expression of ohr that encodes an organic peroxide specific peroxiredoxin. Here, we show that ospR mediated gpx expression, like ohrR and ohr, specifically responds to organic hydroperoxides as compar...

In recent decades, fuel cells have been widely used in energy generation. In a PEMFC, considering the specific application, two types of oxidants are used. Durability tests, which are highly costly products,  are of crucial importance in evaluating the lifetime of fuel cells. The purpose of the present paper is to investigate the performance of a fuel cell by changing the type of oxidant from a...

In 2009, we identified a TCE plume at an abandoned landfill that was located in a low permeable silty-clay aquifer. To treat the TCE, we manufactured slow-release potassium permanganate cylinders (oxidant candles) that had diameters of either 5.1 or 7.6 cm and were 91.4 cm long. In 2010, we compared two methods of candle installation by inserting equal masses of the oxidant candles (7.6-cm vs 5...

Potassium perruthenate (KRuO4), a known, effective oxidant for the conversion of primary and secondary alcohols into carbonyl compounds is impregnated into zeolite X and shown to be a shape-selective oxidant using benzyl alcohol (reacted) and pyrenemethanol (not reacted).