background: use of hormone replacement therapy (hrt) may increase the risk of adult-onset asthma in women. various in vitro studies have reported that estradiol stimulates human mast cell lines causing release of allergic mediators which was not observed in estrogen receptor-alpha (er-alpha) knockout mice. thus, estrogen might be a key element in occurrence of asthma. in the present study, we p...

leiomyomatosis peritonealis disseminata is a very rare condition characterized by the development of multiple smooth muscle-like nodules in the peritoneal cavity. it is associated with increased serum levels of gonadal steroids. the present report describes a 29-year-old patient underwent transabdominal hysterectomy and bilateral salpingo oophorectomy six years ago because of leiomyomatosis per...

OBJECTIVE Adult onset GH deficiency (GHD) is characterized by abnormalities of serum lipoprotein profiles and GH replacement results in favourable alterations in serum total and low density lipoprotein (LDL)-cholesterol. Preliminary evidence has indicated that the effect of GH replacement in this respect may be additive to that of HMG CoA reductase inhibitor (statin) therapy. We have examined t...

this research was conducted to evaluate the effects of synthetic methionine replacement with herbal methionine (hm) on performance, blood biochemical parameters and carcass characteristics in broiler chicken. a total of 280 8-old ross 308 male chicken were randomly assigned to 7 dietary treatments: control, in which 100% methionine requirement was supplied form dl-methionine, and in treatments ...

Background: Serum insulin variations are occasionally observed in patients suffering infertility or gonad failure. The main purpose of the present study was to clarify the effects of gonadectomy and sex steroid hormone replacement on serum insulin level in rats. Materials and Methods: Male rats were divided into control, orchidectomized, and testosterone receiving orchidectomized animals. Femal...

BACKGROUND None of the existing options for long-term testosterone replacement therapy (TRT) for hypogonadal men are ideal. Depot replacement at frequent intervals and implants are effective but invasive and inconvenient for the patient. Oral therapy results in poor hormone levels. Both are associated with undesirable metabolic changes. A transdermal formulation therefore represents a potential...

Leiomyomatosis peritonealis disseminata is a very rare condition characterized by the development of multiple smooth muscle-like nodules in the peritoneal cavity. It is associated with increased serum levels of gonadal steroids. The present report describes a 29-year-old patient underwent transabdominal hysterectomy and Bilateral Salpingo oophorectomy six years ago because of leiomyomatosis per...

A 60-day feeding trial was conducted to evaluate the potential of using poultry by-product meal (PBM) as a partial replacement for fish meal (FM) in the diets for juvenile sobaity. Six iso-nitrogenous and iso-lipidic diets were formulated to contain graded levels of PBM, at 0 (as control diet), 15, 25, 35, 45, and 55% of FM replacement. Each diet was fed to groups of 20 juvenile sobaity in trip...

Out-of-distribution (OOD) detection can be used in deep learning-based applications to reject outlier samples from being unreliably classified by neural networks. Learning classify between OOD and in-distribution is difficult because data comprising the former extremely diverse. It has been observed that an auxiliary dataset most effective training a ``rejection'' network when its are semantica...

OBJECTIVE Fibroblast growth factor 23 (FGF23), a phosphatonin, inhibits renal phosphate reabsorption and suppresses 1-α hydroxylase activity. Calcitriol stimulates FGF23 synthesis in bone. We aimed to determine the effect of vitamin D replacement therapy on serum FGF23 concentrations in vitamin D-deficient women and to compare the FGF23 concentrations of vitamin D-deficient patients with health...