Positron emission tomography (PET) is a popular research topic. People are becoming more interested in PET images as they become widely available. However, the partial volume effect (PVE) remains one of most influential factors causing resolution to degrade. It possible reduce this PVE and achieve better image quality by measuring modeling point spread function (PSF) then accounting for it insi...

We have developed an image quality theory for reconstruction that we apply to filtered back-projection (FBP) and statistical reconstruction (OSEM) for Single Photon Emission Computed Tomography (SPECT). Quantitative measures of reconstruction performance are given in terms of signal and noise power spectra, SPS and NPS, that we derive from phantom images. This allows evaluating the properties o...

UNLABELLED Gated SPECT recorded with 16 intervals determines left ventricular (LV) ejection fraction more accurately than does gated SPECT recorded with 8 intervals but produces higher image noise. This study aimed to assess the results from sestamibi and (201)Tl 16-interval gated SPECT when both signal-to-noise ratio and spatial resolution were enhanced with an original method of reconstructio...

UNLABELLED The aim of this work was to compare the quantitative accuracy of iteratively reconstructed cardiac (18)F-FDG PET with that of filtered backprojection for both 2-dimensional (2D) and 3-dimensional (3D) acquisitions and to establish an optimal procedure for imaging myocardial viability with (18)F-FDG PET. METHODS Eight patients underwent dynamic cardiac (18)F-FDG PET using an interle...

OBJECTIVE PET imaging is possible with copper (Cu) isotopes, (60)Cu, (61)Cu, (62)Cu and (64)Cu. Although (62)Cu- and (64)Cu-labeled radiotracers are often used for preclinical and clinical PET studies, we do not know which radiotracers have better image quality for tumor imaging. In this study, we compare image quality between (62)Cu and (64)Cu imaging with a different acquisition mode and reco...

BACKGROUND The clinical validation of the EARL harmonization program for standardised uptake value (SUV) metrics is well documented; however, its potential for defining metabolic active tumour volume (MATV) has not yet been investigated. We aimed to compare delineation of MATV on images reconstructed using conventional ordered subset expectation maximisation (OSEM) with those reconstructed usin...

Abstract Background Image quality and quantitative accuracy of positron emission tomography (PET) depend on several factors such as uptake time, scanner characteristics image reconstruction methods. Ordered subset expectation maximization (OSEM) is considered the gold standard for reconstruction. Penalized-likelihood estimation (PL) algorithms have been recently developed PET to improve quantit...

Iterative reconstructions for clinical PET must run fast. We describe a clinical processing method based on sinogram rebinning, Fourier rebinning for the 3D to 2D data reduction, and iterative reconstruction using the attenuation-weighted OSEM method with a projector based on a gaussian pixel model. When this approach is used, multi-bed clinical oncology scans can be ready for diagnosis within ...