An orthopedic hardware infection with Clostridium disporicum is described. C. disporicum is a gram positive anaerobic bacillus which can contain two subterminal spores. C. disporicum had not previously been reported in musculoskeletal infections. Gram stains demonstrating gram positive bacilli with two subterminal spores should alert practitioners to the possibility of C. disporicum infection.

Microbial identification of orthopedic implant-associated infections using sonication fluid (SF) submitted to a concentration step by membrane filtration (SMF) was compared with the standard centrifugation (SC) method. Among 33 retrieved infected implants, sonication identified microorganisms in 26 (78.8%). The sensitivity of SC was higher than that of SMF (78.8% versus 30.3%; P < 0.001).

Background. Patients on chronic minocycline suppression for orthopedic infections at a single institution were studied for development of minocycline-induced cutaneous hyperpigmentation and analysis of risk factors. Methods. This is a retrospective cohort study of Mayo Clinic patients with hardware or non-hardware associated chronic orthopedic infections treated with long termminocycline suppre...

Titanium (Ti) and titanium alloy have been widely used in orthopedics. However, the successful application of implants is mainly limited due to implant-associated infections. The implant surface contributes osseointegration, but also has risk accelerating growth bacterial colonies, surfaces infected with bacteria easily form biofilms that are resistant antibiotics. Biofilm-related infections a ...

BACKGROUND Indwelling urinary catheter duration is an important risk factor for catheter-associated urinary tract infections (CAUTIs). OBJECTIVE To audit patient-level postoperative catheter duration and measure the impact of its feedback to nursing staff on postoperative catheter duration and CAUTI rates. DESIGN Preobservational and postobservational study. SETTING Two surgical units at ...

Background: The incidence of placement of osteosynthetic materials has grown worldwide. Bioabsorbable materials are more commonly used now days in Orthopedic surgeries. Implants modify the risk of infection by bacterial adhesion, tissue integration, and immunomodulation. Bacterial adhesion to implant leads to interaction between bacteria and implant. Aim: To evaluate the incidence of infections...

INTRODUCTION Implant-associated infection, although rare, has been one of main complications accompanied by orthopedic implant surgeries including prosthetic joint replacement and fracture fixation. The number of such infections has continuously increased with growing demands for surgical implantation due to population aging and increased participation in outdoor activities. The established inf...

ubiquicidin (ubi) [29-41] is a synthetic cationic antimicrobial peptide that preferentially binds to bacterial cell membrane at the site of infection. we aimed to assess diagnostic value of 99mtc-ubi [29-41] as a radiopharmaceutical in differentiation of bacterial infection from sterile inflammation in suspected orthopedic implants. nine patients suspected for orthopedic implant infection, all ...