The aim of present study is to exist a novel super disintegrants in fast dissolving tablet. Guar gum is a natural substance and used in many pharmaceutical product and it can also used as a super disintegrating agent in fast dissolving tablet. The result is that it released the 99.21% drug in 15min as compared to Sodium Starch Glycolate (SSG), where only 97.51% drug was released. The onset of t...

The aim and objective of orally disintegrating tablets by direct compression method was emerged from desired to provide patient with a conventional mean of taking their medication. Difficulty in swallowing (Dysphagia) is a common problem of all age groups, especially elderly and pediatrics, because of physiological changes associated with these groups of patients. In the present work Ondansetro...

Pramipexole is the mostly prescribed drug in patients with Parkinson disease. The incidence of Parkinson disease is related to aging and mostly developed in elderly people with difficulty in swallowing or dysphagia. In the current study we aimed to develop an orally fast disintegrating tablet (ODT) of pramipexole as a preferable alternative in geriatric patients. Hence, the fast disintegration ...

The aim of this study was to prepare, using taste-masked granules, tablets which can rapidly disintegrate in saliva (rapidly disintegrating tablet), of drugs with bitter taste (pirenzepine HCl or oxybutynin HCl). The taste-masked granules were prepared using aminoalkyl methacrylate copolymers (Eudragit E-100) by the extrusion method. None of the drugs dissolved from the granules (% of dissolved...

An antipyretic analgesic drug called paracetamol is used in children to treat mild moderate pain and fever. Orally Disintegrating Tablet (ODT), a medicine that dissolves seconds, was created help who have difficulty swallowing tablets. The purpose of this study determine the effect changes concentration chitosan as disintegrant formulation ODT paracetamol. These tablets are made using wet granu...

The demand for FDT (Fast Disintegrating Tablet) has been increasing from the last decade particularly in geriatric, pediatric and patient with some sort of disabilities in swallowing. FDTs are those tablets which when placed in mouth get dissolved rapidly in saliva without the need of liquid and can be swallowed. European pharmacopoeia adopted the term Orodispersible tablet for FDTs. Fast disin...