background: normal tissue toxicity continues to remain as a major challenge for radiation oncologists for delivering the total dose to the tumour cells in cancer patients. cellular, molecular and plasma based early biomarkers to predict the overreactions and non-overreactions of normal tissue toxicity before the initiation of radiotherapy can be valuable for personalised treatment. the aim of t...

Despite Euphorbia hirta L. ethnomedicinal benefits, very few studies have described the potential toxicity. The aim of the present study was to evaluate the in vivo toxicity of methanolic extracts of E. hirta. The acute and subchronic oral toxicity of E. hirta was evaluated in Sprague Dawley rats. The extract at a single dose of 5,000 mg/kg did not produce treatment related signs of toxicity or...

The outcome of avian field studies was examined to model the likelihood of mortality. The data were divided into clusters reflecting the type of pesticide application and bird guilds present on site. Logistic regression was used to model the probability of a bird kill. Four independent variables were tested for their explanatory power: a variable reflecting acute oral toxicity and application r...

Zingiber cassumunar Roxb. has been used for traditional medicine, but few studies have described its potential toxicity. In this study, the acute and chronic oral toxicity of Z. cassumunar extract granules were evaluated in Sprague-Dawley rats. The extract at a single dose of 5000 mg/kg body weight did not produce treatment related signs of toxicity or mortality in any of the animals tested dur...

Oral administration of (20 mg/ml), Acetamidine the active ingradiant mospilan 20SG , neonicotinoid insecticide that is effective against both soil and plant insects (LD50=200mg\kg), for 30 days in male albino mice aged (6-7weeks), resulted Histopathologically significant alterations lungs included marked. Haemorrhage inflammatory cells infiltration thickening connective tissue stroma. The oral ...

Chronic lead poisoning has traditionally been treated by parenteral agents. We present a case where a comparison of ethylene diaminetetra-acetic acid was made with 2,3-dimethyl succinic acid (DMSA) which has the advantage of oral administration associated with little toxicity and appeared to be at least as efficacious.