We report here the history and evolution of the use of oral mucosa in reconstructive urethral surgery since it was first used for urethroplasty in 1894. Since that time, many authors have contributed to develop, improve and popularize the use of oral mucosa as a substitute material. Paediatric urologists should be considered pioneers on the use of oral mucosa as they used it to repair primary a...

AIM This study evaluated the behavior of oral epithelial cells in contact with orthodontic appliances. METHODS Oral epithelial cells of clinically normal buccal mucosa were obtained by liquid-based exfoliative cytology from 22 orthodontic patients. The following regions were evaluated: a) oral mucosa exposed to friction from orthodontic brackets; b) oral mucosa exposed to friction from the tu...

Human and simian immunodeficiency virus (HIV and SIV) infections are characterized by manifestation of numerous opportunistic infections and inflammatory conditions in the oral mucosa. The loss of CD4(+) T cells that play a critical role in maintaining mucosal immunity likely contributes to this process. Here we show that CD4(+) T cells constitute a minor population of T cells in the oral mucos...

Tissue engineering of bone and oral mucosa have been extensively studied independently. The aim of this study was to develop and investigate a novel combination of bone and oral mucosa in a single 3D in vitro composite tissue mimicking the natural structure of alveolar bone with an overlying oral mucosa. Rat osteosarcoma (ROS) cells were seeded into a hydroxyapatite/tri-calcium phosphate scaffo...

BACKGROUND Urethral reconstruction has continued to present formidable and enormous challenges for urologic, paediatric and plastic surgeons as diverse opinions have been expressed on the quality and type of ideal substitution material. This literature review is aimed at drawing attention of surgeons to the versatile nature of oral mucosal grafts. METHODS A review of the utilization of oral m...

background: superficial mucocele presents as small, clear vesicle on noninflamed mucosa. in this study, we report several vesicles on the bucal mucosa of a woman diagnosed as superficial mucocele.case presentation: a 48-year old woman presented with multiple vesicles on her labial mucosa, ventral surface of the tongue, floor of the mouth and palate. a mucosal biopsy was taken from the vesicle. ...

background and aims. many oral squamous cell carcinomas develop from potentially malignant disorders (pmds) which include a variety of lesions and conditions characterized by an increased risk for malignant transformation. this study evaluated the quantitative expression of egfr in normal oral mucosa, oral leukoplakia and oral submucous fibrosis to predict the malignant risk in compliance with ...

Background and Aim: Lichen planus is an inflammatory autoimmune mucocutaneous disease. Stimulation of T cells and antigen-presenting cells (APCs), such as dendritic cells, mediates apoptosis of keratinocytes and basement membrane destruction. The aim of this study was to investigate the expression of one of the immune cell markers (CD86) in erosive oral lichen planus. Materials and Methods: In...

OBJECTIVES Transient receptor potential cation channel (subfamily V, members 1-4) (TRPV1-4) are expressed in skin and neurons and activated by external stimuli in normal mucosae of all oral cavity sites. The oral cavity is exposed to various stimuli, including temperature, mechanical stimuli, chemical substances, and changes in pH, and, notably, the risk factors for oncogenic transformation in ...

Precancerous lesions of oral mucosa, known as potentially malignant disorders in recent years, are consists a group diseases, which should be diagnosed the early stage. Oral leukoplakia, submucous fibrosis, and erythroplakia most common mucosal diseases that have very high transformation rate.