Open-field behavioral assays are commonly used to test both locomotor activity and emotionality in rodents. We performed open-field tests on house mice (Mus domesticus) from four replicate lines genetically selected for high voluntary wheel-running for 22 generations and from four replicate random-bred control lines. Individual mice were recorded by video camera for 3 min in a 1-m2 open-field a...

the methanolic leaf extract of thuja occidentalis was evaluated for possible sedative activities in mice. sedative activity was evaluated by using hole cross, open field, thiopental sodium-induced sleeping time and elevated-plus maze (epm) tests at 200mg/kg and 400 mg/kg.  the extract decreased the locomotor activity of mice in hole cross, open field and epm test and showed the remarkable resul...

The present study was conducted to investigate the possible anxiolytic and sedative ofan acute administration and 4-day repeated dosing of an aqueous extract of flowers of Alceaaucheri (Boiss.) Alef. (EFA) in rats subjected to the elevated plus-maze (EPM), open-field, andhorizontal wire tests. All drugs were administered intraperitoneally. Phytochemical screeningconfirmed the presence of phenol...

SME innovation strategy and motivation has become one of the most challenging subjects of innovation policy. New innovation models proposed recently have captured the attention of policy makers. However, these models seem for the most part to be applicable to medium-sized or large enterprises. The objective of this paper is to analyse the open innovation model in the case of outsourced cooperat...

Open channel junction is one of the most common hydraulic structures that are used in various practical situations such as sewer, drainage, and flood control systems. Knowing the fluid flow behavior, is one of the most important topics in designing the efficient open channel junctions. The complexity and deviation of flow in the junction’s zone disrupts the proper functioning of the flowmeter d...

The Open Force Field (OpenFF) Initiative develops open, reproducible force fields for atomistic molecular simulations as well automated infrastructure and systematic methodology their parametrization validation. Here we describe the extension of OpenFF to support biopolymers, enabling both small molecules biopolymers with a self-consistent field. workflow includes QCSubmit submission curation q...

The present study was conducted to investigate the possible anxiolytic and sedative ofan acute administration and 4-day repeated dosing of an aqueous extract of flowers of Alceaaucheri (Boiss.) Alef. (EFA) in rats subjected to the elevated plus-maze (EPM), open-field, andhorizontal wire tests. All drugs were administered intraperitoneally. Phytochemical screeningconfirmed the presence of phenol...

provides an overview of subject repositories (srs) throughout the world in response to the open access movement (oam). it mainly highlights the current trends of repository development in library and information science (lis) field. this paper covers all repositories in lis field as registered in opendoar (directory of open access repository) database. the main objective of the paper is to sele...